Glutamate is the most important excitatory neurotransmitter of the mammalian central
nervous system (CNS), playing an important role in memory, synaptic plasticity and neuronal …

Several important and previously unrecognized roles for the neurotransmitter glutamate in
the biology of primary brain tumors have recently been elucidated. Glutamate is produced …

We examined the regulation of glutamate transporter protein expression after stimulation
with selective metabotropic glutamate receptor (mGluR) agonists in cultured human glial …

Glutamate, a nonessential amino acid, is a major bioenergetic substrate for proliferating
normal and neoplastic cells on one hand and an excitatory neurotransmitter that is actively …

Glioblastoma (GBM) is the most common and malignant form of primary brain tumor with a
median survival time of 14–16 months in GBM patients. Surgical treatment with …

There is now compelling evidence that the excitatory amino acid neurotransmitter glutamate
plays a pivotal role in drug addiction and alcoholism. As a result, there has been increasing …

Stimulation of Group I metabotropic glutamate receptors (mGluR1 and mGluR5) leads to
activation of a wide variety of signalling pathways. mGluRs couple to Gαq/11 proteins …

High-affinity glutamate transporters ensure termination of glutamatergic neurotransmission
and keep the synaptic concentration of this amino acid below excitotoxic levels. However …

Glioneuronal tumours are an increasingly recognized cause of chronic pharmaco‐resistant
epilepsy. In the present study the immunocytochemical expression of various glutamate …

Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system
(CNS) and exerts its actions via a number of ionotropic glutamate receptors/channels and …