Attention-deficit hyperactivity disorder (ADHD) is a prevalent and debilitating disorder
diagnosed on the basis of persistent and developmentally-inappropriate levels of …

notwithstanding the many strengths of the dynamic developmental theory, there remain
challenges to be overcome before it can be incorporated into a true causal model of …

The mesocorticolimbic dopamine system, which arises in the ventral tegmental area and
innervates the nucleus accumbens, among numerous other regions, has been implicated in …

Rationale Activation of “co-agonist” N-methyl-d-aspartate (NMDA) and Glycine B sites is
mandatory for the operation of NMDA receptors, which play an important role in the control …

Prenatal stress greatly influences the ability of an individual to manage stressful events in
adulthood. Such vulnerability may result from abnormalities in the development and …

Functional interactions between dopaminergic neurotransmission and glutamatergic
neurotransmission are well known to play a crucial integrative role in the striatum, the major …

RUSSELL, VA Dopamine hypofunction possibly results from a defect in glutamate-
stimulated release of dopamine in the nucleus accumbens shell of a rat model for attention …

Endocannabinoids are emerging as potent modulators of neuronal activity throughout the
brain, and activation of the type-1 cannabinoid receptor (CB1R) reduces sensory-evoked …

The present study sought to integrate convergent lines of research on the associations
among the dopamine D4 receptor (DRD4) gene, novelty seeking and drinking behaviors …

Purpose: Since the description of his original patient Auguste D. with cognitive disability,
Alois Alzheimer persisted in his clinical investigations to understand this complex disease …