CLC chloride channels and transporters: structure, function, physiology, and disease
TJ Jentsch, M Pusch - Physiological reviews, 2018 - journals.physiology.org
CLC anion transporters are found in all phyla and form a gene family of eight members in
mammals. Two CLC proteins, each of which completely contains an ion translocation …
mammals. Two CLC proteins, each of which completely contains an ion translocation …
Leukodystrophies: a proposed classification system based on pathological changes and pathogenetic mechanisms
MS Van der Knaap, M Bugiani - Acta neuropathologica, 2017 - Springer
Leukodystrophies are genetically determined disorders characterized by the selective
involvement of the central nervous system white matter. Onset may be at any age, from …
involvement of the central nervous system white matter. Onset may be at any age, from …
[HTML][HTML] HepaCAM controls astrocyte self-organization and coupling
Astrocytes extensively infiltrate the neuropil to regulate critical aspects of synaptic
development and function. This process is regulated by transcellular interactions between …
development and function. This process is regulated by transcellular interactions between …
Astrocytes in the regulation of cerebrovascular functions
M Cohen‐Salmon, L Slaoui, N Mazaré, A Gilbert… - Glia, 2021 - Wiley Online Library
Astrocytes are the most numerous type of neuroglia in the brain and have a predominant
influence on the cerebrovascular system; they control perivascular homeostasis, the integrity …
influence on the cerebrovascular system; they control perivascular homeostasis, the integrity …
Heterogeneity of white matter astrocytes in the human brain
M Bugiani, BC Plug, JHK Man, M Breur… - Acta …, 2022 - Springer
Astrocytes regulate central nervous system development, maintain its homeostasis and
orchestrate repair upon injury. Emerging evidence support functional specialization of …
orchestrate repair upon injury. Emerging evidence support functional specialization of …
Discovery of CLC transport proteins: cloning, structure, function and pathophysiology
TJ Jentsch - The Journal of physiology, 2015 - Wiley Online Library
After providing a personal description of the convoluted path leading 25 years ago to the
molecular identification of the Torpedo Cl− channel ClC‐0 and the discovery of the CLC …
molecular identification of the Torpedo Cl− channel ClC‐0 and the discovery of the CLC …
Metachromatic leukodystrophy and transplantation: Remyelination, no cross‐correction
NI Wolf, M Breur, B Plug, S Beerepoot… - Annals of clinical …, 2020 - Wiley Online Library
Objective In metachromatic leukodystrophy, a lysosomal storage disorder due to decreased
arylsulfatase A activity, hematopoietic stem cell transplantation may stop brain …
arylsulfatase A activity, hematopoietic stem cell transplantation may stop brain …
Aquaporin-4 and GPRC5B: old and new players in controlling brain oedema
EMJ Passchier, S Kerst, E Brouwers, EMC Hamilton… - Brain, 2023 - academic.oup.com
Brain oedema is a life-threatening complication of various neurological conditions.
Understanding molecular mechanisms of brain volume regulation is critical for therapy …
Understanding molecular mechanisms of brain volume regulation is critical for therapy …
Mlc1-Expressing Perivascular Astrocytes Promote Blood–Brain Barrier Integrity
In the mammalian brain, perivascular astrocytes (PAs) closely juxtapose blood vessels and
are postulated to have important roles in the control of vascular physiology, including …
are postulated to have important roles in the control of vascular physiology, including …
Astrocyte–oligodendrocyte–microglia crosstalk in astrocytopathies
DM de Waard, M Bugiani - Frontiers in cellular neuroscience, 2020 - frontiersin.org
Defective astrocyte function due to a genetic mutation can have major consequences for
microglia and oligodendrocyte physiology, which in turn affects the white matter integrity of …
microglia and oligodendrocyte physiology, which in turn affects the white matter integrity of …