Towards an understanding of psychedelic-induced neuroplasticity

AE Calder, G Hasler - Neuropsychopharmacology, 2023 - nature.com
Classic psychedelics, such as LSD, psilocybin, and the DMT-containing beverage
ayahuasca, show some potential to treat depression, anxiety, and addiction. Importantly …

Neuroplasticity as a convergent mechanism of ketamine and classical psychedelics

LR Aleksandrova, AG Phillips - Trends in pharmacological sciences, 2021 - cell.com
The emerging therapeutic efficacy of ketamine and classical psychedelics for depression
has inspired tremendous interest in the underlying neurobiological mechanisms. We review …

[HTML][HTML] Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo

LX Shao, C Liao, I Gregg, PA Davoudian, NK Savalia… - Neuron, 2021 - cell.com
Psilocybin is a serotonergic psychedelic with untapped therapeutic potential. There are hints
that the use of psychedelics can produce neural adaptations, although the extent and …

Photocurable bioresorbable adhesives as functional interfaces between flexible bioelectronic devices and soft biological tissues

Q Yang, T Wei, RT Yin, M Wu, Y Xu, J Koo, YS Choi… - Nature materials, 2021 - nature.com
Flexible electronic/optoelectronic systems that can intimately integrate onto the surfaces of
vital organ systems have the potential to offer revolutionary diagnostic and therapeutic …

Wireless multilateral devices for optogenetic studies of individual and social behaviors

Y Yang, M Wu, A Vázquez-Guardado… - Nature …, 2021 - nature.com
Advanced technologies for controlled delivery of light to targeted locations in biological
tissues are essential to neuroscience research that applies optogenetics in animal models …

Synaptic mechanisms regulating mood state transitions in depression

PK Parekh, SB Johnson, C Liston - Annual Review of …, 2022 - annualreviews.org
Depression is an episodic form of mental illness characterized by mood state transitions with
poorly understood neurobiological mechanisms. Antidepressants reverse the effects of …

Shared and distinct brain regions targeted for immediate early gene expression by ketamine and psilocybin

PA Davoudian, LX Shao, AC Kwan - ACS Chemical Neuroscience, 2023 - ACS Publications
Psilocybin is a psychedelic with therapeutic potential. While there is growing evidence that
psilocybin exerts its beneficial effects through enhancing neural plasticity, the exact brain …

Wireless multi-lateral optofluidic microsystems for real-time programmable optogenetics and photopharmacology

Y Wu, M Wu, A Vázquez-Guardado, J Kim… - Nature …, 2022 - nature.com
In vivo optogenetics and photopharmacology are two techniques for controlling neuronal
activity that have immense potential in neuroscience research. Their applications in tether …

Ketamine and serotonergic psychedelics: an update on the mechanisms and biosignatures underlying rapid-acting antidepressant treatment

JN Johnston, B Kadriu, J Allen, JR Gilbert, ID Henter… - …, 2023 - Elsevier
The discovery of ketamine as a rapid-acting antidepressant spurred significant research to
understand its underlying mechanisms of action and to identify other novel compounds that …

Unraveling the dynamics of dopamine release and its actions on target cells

T Sippy, NX Tritsch - Trends in neurosciences, 2023 - cell.com
The neuromodulator dopamine (DA) is essential for regulating learning, motivation, and
movement. Despite its importance, however, the mechanisms by which DA influences the …