The roles of microRNAs on tuberculosis infection: meaning or myth?
The central proteins for protection against tuberculosis are attributed to interferon-γ, tumor
necrosis factor-α, interleukin (IL)-6 and IL-1β, while IL-10 primarily suppresses anti …
necrosis factor-α, interleukin (IL)-6 and IL-1β, while IL-10 primarily suppresses anti …
Altered microRNA expression levels in mononuclear cells of patients with pulmonary and pleural tuberculosis and their relation with components of the immune …
SV Spinelli, A Diaz, L D'Attilio, MM Marchesini… - Molecular …, 2013 - Elsevier
Different lines of evidence demonstrate that microRNAs (miRNAs) play an important role in
host–pathogen interactions. In this study we investigated the expression patterns of several …
host–pathogen interactions. In this study we investigated the expression patterns of several …
The Immunoregulatory Actions of DHEA in Tuberculosis, A Tool for Therapeutic Intervention?
B Bongiovanni, A Díaz, N Santucci… - Frontiers in …, 2022 - frontiersin.org
Dehydroepiandrosterone (DHEA) is an androgen synthesized by the adrenal cortex, which
is an intermediary in the biosynthesis of sex hormones, such as testosterone and estradiol …
is an intermediary in the biosynthesis of sex hormones, such as testosterone and estradiol …
Steroid hormone modulates the production of cathelicidin and human β-defensins in lung epithelial cells and macrophages promoting Mycobacterium tuberculosis …
SP Marin-Luevano, A Rodriguez-Carlos… - Tuberculosis, 2021 - Elsevier
Several studies have documented the interaction between the immune and endocrine
systems as an effective defense strategy against tuberculosis, involving the production of …
systems as an effective defense strategy against tuberculosis, involving the production of …
The implication of pro-inflammatory cytokines in the impaired production of gonadal androgens by patients with pulmonary tuberculosis
EI Bini, L D'Attilio, B Marquina-Castillo… - tuberculosis, 2015 - Elsevier
Background The chronic nature of tuberculosis and the protracted immuno-inflammatory
reactions are implied in a series of metabolic and immune-endocrine changes …
reactions are implied in a series of metabolic and immune-endocrine changes …
The ESX-1 virulence factors downregulate miR-147-3p in Mycobacterium marinum-infected macrophages
X Zuo, L Wang, Y Bao, J Sun - Infection and Immunity, 2020 - Am Soc Microbiol
As important virulence factors of Mycobacterium tuberculosis, EsxA and EsxB not only play a
role in phagosome rupture and M. tuberculosis cytosolic translocation but also function as …
role in phagosome rupture and M. tuberculosis cytosolic translocation but also function as …
Effect of cortisol and/or DHEA on THP1-derived macrophages infected with Mycobacterium tuberculosis
B Bongiovanni, D Mata-Espinosa, L D'Attilio… - Tuberculosis, 2015 - Elsevier
Tuberculosis (TB) is a major health problem requiring an appropriate cell immune response
to be controlled. Macrophages play a central role in the response against Mycobacterium …
to be controlled. Macrophages play a central role in the response against Mycobacterium …
The association between tuberculosis and the development of insulin resistance in adults with pulmonary tuberculosis in the Western sub-district of the Cape …
L Philips, J Visser, D Nel, R Blaauw - BMC infectious diseases, 2017 - Springer
Background The existence of a bi-directional relationship between tuberculosis (TB) and
insulin resistance (IR)/diabetes has been alluded to in literature. Although diabetes has …
insulin resistance (IR)/diabetes has been alluded to in literature. Although diabetes has …
Evidence for a more disrupted immune-endocrine relation and cortisol immunologic influences in the context of tuberculosis and type 2 diabetes comorbidity
RDV Fernández, A Díaz, B Bongiovanni… - Frontiers in …, 2020 - frontiersin.org
Pulmonary tuberculosis (PTB), caused by Mycobacterium tuberculosis (Mtb), is a major
health problem worldwide, further aggravated by the convergence of type 2 diabetes …
health problem worldwide, further aggravated by the convergence of type 2 diabetes …
Hair levels of steroid, endocannabinoid, and the ratio biomarkers predict viral suppression among people living with HIV/AIDS in China
L Chu, S Liu, Y Wu, J Yang, S Qiao, Y Zhou, H Deng… - Clinica Chimica …, 2022 - Elsevier
Background Predicting viral suppression early is crucial to improving treatment outcomes
among people living with HIV/AIDS (PLWH) in clinics. Viral suppression is affected by stress …
among people living with HIV/AIDS (PLWH) in clinics. Viral suppression is affected by stress …