Mechanisms of thrombogenesis in atrial fibrillation: Virchow's triad revisited

T Watson, E Shantsila, GYH Lip - The Lancet, 2009 - thelancet.com
Atrial fibrillation is the most common sustained cardiac arrhythmia, which is associated with
a high risk of stroke and thromboembolism. Increasing evidence suggests that the …

The prothrombotic state in atrial fibrillation: pathophysiological and management implications

AA Khan, GYH Lip - Cardiovascular research, 2019 - academic.oup.com
Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia and is associated with
significant morbidity and mortality. There is plenty of evidence available to support the …

Effect of clopidogrel added to aspirin in patients with atrial fibrillation

Active Investigators - New England Journal of Medicine, 2009 - Mass Medical Soc
Background Vitamin K antagonists reduce the risk of stroke in patients with atrial fibrillation
but are considered unsuitable in many patients, who usually receive aspirin instead. We …

Effect of atrial fibrillation on atrial thrombogenesis in humans: impact of rate and rhythm

HS Lim, SR Willoughby, C Schultz, C Gan… - Journal of the American …, 2013 - jacc.org
Objectives: We sought to assess the effect of atrial fibrillation (AF) on atrial thrombogenesis
in humans by determining the impact of rate and rhythm. Background: Although AF is known …

The left atrial appendage: from embryology to prevention of thromboembolism

G Patti, V Pengo, R Marcucci, P Cirillo… - European Heart …, 2017 - academic.oup.com
The left atrial appendage (LAA) is the main source of thromboembolism in patients with non-
valvular atrial fibrillation (AF). As such, the LAA can be the target of specific occluding device …

Acute onset human atrial fibrillation is associated with local cardiac platelet activation and endothelial dysfunction

JG Akar, W Jeske, DJ Wilber - Journal of the American College of …, 2008 - jacc.org
Objectives: The purpose of this study was to determine whether acute onset atrial fibrillation
(AF), independent of other risk factors, predisposes to an early prothrombotic state …

[HTML][HTML] Association of hemostatic markers with atrial fibrillation: a meta-analysis and meta-regression

N Wu, S Tong, Y Xiang, L Wu, B Xu, Y Zhang, X Ma… - PLoS …, 2015 - journals.plos.org
Background There is growing evidence that indicates the presence of a prothrombotic state
in atrial fibrillation (AF). However, the role of hemostatic markers in AF remains inconclusive …

Mean platelet volume is elevated during paroxysmal atrial fibrillation: a marker of increased platelet activation?

Y Colkesen, T Acil, B Abayli, F Yigit… - Blood coagulation & …, 2008 - journals.lww.com
Paroxysmal atrial fibrillation might be a risk factor for stroke such as chronic atrial fibrillation.
We examined the relation between mean platelet volume and paroxysmal atrial fibrillation to …

Inflammatory cytokines and atrial fibrillation: current and prospective views

HAR Hadi, AA Alsheikh-Ali… - Journal of …, 2010 - Taylor & Francis
Atrial fibrillation (AF) is the most common sustained arrhythmia and a challenging clinical
problem encountered in daily clinical practice. There is an increasing body of evidence …

Mean platelet volume in patients with nonvalvular atrial fibrillation

G Tekin, YK Tekin, N Sivri, E Yetkin - Blood Coagulation & …, 2013 - journals.lww.com
The procoagulant and prothrombotic states in patients with chronic atrial fibrillation are
higher than those in patients with normal sinus rhythm. Mean platelet volume (MPV) which is …