Liver flukes include Fasciola hepatica, Fasciola gigantica, Clonorchis sinensis, Opisthorchis
spp., Fascioloides magna, Gigantocotyle explanatum and Dicrocoelium spp. The two main …

Fasciolosis caused by the liver flukes Fasciola hepatica and Fasciola gigantica is one of the
most important neglected parasitic diseases of humans and animals. The ability of the …

Triclabendazole (TCBZ) is the only chemical that kills early immature and adult Fasciola
hepatica (liver fluke) but widespread resistance to the drug greatly compromises fluke …

Fasciola hepatica is a trematode parasite with a global distribution, which is responsible for
considerable disease and production losses in a range of food producing species. It is also …

Fasciolosis, a food‐borne trematodiasis, results following infection with the parasites,
Fasciola hepatica and Fasciola gigantica. These trematodes greatly affect the global …

Extracellular vesicles (EVs) released by parasites have important roles in establishing and
maintaining infection. Analysis of the soluble and vesicular secretions of adult Fasciola …

We briefly review cysteine proteases (orthologs of mammalian cathepsins B, L, F, and C)
that are expressed in flatworm and nematode parasites. Emphasis is placed on enzyme …

Fasciola hepatica is a well-known helminth parasite, with significant economic and public
health importance all over the world. It has been known since more than 630 years ago and …

Parasite-released extracellular vesicles (EVs) deliver signals to the host immune system that
are critical to maintaining the long-term relationship between parasite and host. In the …

Background The major pathogenesis associated with Fasciola hepatica infection results
from the extensive tissue damage caused by the tunnelling and feeding activity of immature …