Periodontitis and other bone loss diseases, decreasing bone volume and strength, have a
significant impact on millions of people with the risk of tooth loss and bone fracture. The …

Aim Periodontitis is an inflammatory disease that destroys both soft and hard periodontal
tissues. However, a complex periodontal cytokine network remains unclear. This systematic …

Background Chronic periodontitis (CP), defines as destruction of the supporting tissues of
the teeth and resorption of the alveolar bone. It is widespread in human populations and …

Objective: Pro-inflammatory cytokines, interleukin-6 (IL-6), demonstrated to be suppressed
by interleukin-10 (IL-10) are known to be regulated by the transcription factor nuclear factor …

A decade ago a hypothesis was proposed that, similar to the Bacteria and Eukarya, the
archaeal domain of life might harbor certain species capable of causing disease (Cavicchioli …

Background Periodontitis is a major oral health problem and it is considered as one of the
reasons for tooth loss in developing and developed nations. The objective of the current …

Objectives Several epidemiological studies have evaluated association of interleukin 10 (IL-
10) polymorphisms with risk of periodontitis. However, the results remain conflicting and …

Background: Periodontitis is a common disease with an unclear pathological mechanism.
No precise consensus has been reached to evaluate the association between the IL-10 …

Background Tumour necrosis factor-alpha (TNF-alpha) has been implicated in the
pathogenesis of generalized aggressive periodontitis (AgP) and chronic periodontitis (CP) …

Objective The objective of this meta-analysis was to assess the association between three
interleukin-10 (IL-10) promoter single nucleotide polymorphisms (rs1800871, rs1800872 …