Kidney disease is a leading cause of morbidity and mortality across the globe. Current
interventions for kidney disease include dialysis and renal transplantation, which have …

Chronic kidney disease (CKD) is one of the leading causes of mortality worldwide because
of kidney failure and the associated challenges of its treatment including dialysis and kidney …

Dent disease is a rare renal tubular disease with X-linked recessive inheritance
characterized by low molecular weight proteinuria (LMWP), hypercalciuria, and …

Dent disease (DD) is a hereditary renal disorder characterized by low molecular weight
(LMW) proteinuria and progressive renal failure. Inactivating mutations of the CLCN5 gene …

Dent disease-1 (DD-1) is a rare X-linked tubular disorder characterized by low-molecular-
weight proteinuria (LMWP), hypercalciuria, nephrolithiasis and nephrocalcinosis. This …

Dent disease type 1 is caused by changes in the chloride voltage-gated channel 5 (CLCN5)
gene on chromosome X, resulting in the lack or dysfunction of chloride channel ClC-5 …

Mutations in Cl−/H+ antiporter ClC-5 cause Dent's disease type 1 (DD1), a rare tubulopathy
that progresses to renal fibrosis and kidney failure. Here, we have used DD1 human cellular …

Dent disease type 1 is a rare X-linked recessive inherited renal disorder affecting mainly
young males, generally leading to end-stage renal failure and for which there is no cure. It is …

Dent disease type 1 (Dent 1) is a rare X-linked genetic condition which impacts kidney
function and is caused by pathogenic variants in CLCN5. Affected males typically develop …

Dent disease type 1 is a rare inherited renal disorder affecting mainly young males,
generally leading to end-stage renal failure and for which there is no cure. It is caused by …