Population genomics of Klebsiella pneumoniae

KL Wyres, MMC Lam, KE Holt - Nature Reviews Microbiology, 2020 - nature.com
Klebsiella pneumoniae is a common cause of antimicrobial-resistant opportunistic infections
in hospitalized patients. The species is naturally resistant to penicillins, and members of the …

Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives

JE Choby, J Howard‐Anderson… - Journal of internal …, 2020 - Wiley Online Library
Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a concerning global
pathogen. hvKp is more virulent than classical K. pneumoniae (cKp) and capable of causing …

A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

MMC Lam, RR Wick, SC Watts, LT Cerdeira… - Nature …, 2021 - nature.com
Klebsiella pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-
associated infections, neonatal sepsis and community-acquired liver abscess, and is …

Epidemic of carbapenem-resistant Klebsiella pneumoniae in Europe is driven by nosocomial spread

S David, S Reuter, SR Harris, C Glasner, T Feltwell… - Nature …, 2019 - nature.com
Public health interventions to control the current epidemic of carbapenem-resistant
Klebsiella pneumoniae rely on a comprehensive understanding of its emergence and …

Genomic dissection of Klebsiella pneumoniae infections in hospital patients reveals insights into an opportunistic pathogen

CL Gorrie, M Mirčeta, RR Wick, LM Judd… - Nature …, 2022 - nature.com
Klebsiella pneumoniae is a major cause of opportunistic healthcare-associated infections,
which are increasingly complicated by the presence of extended-spectrum beta-lactamases …

Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

RM Martin, MA Bachman - Frontiers in cellular and infection …, 2018 - frontiersin.org
Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of
plasmids and chromosomal gene loci. This accessory genome divides K. pneumoniae …

Klebsiella pneumoniae: a major worldwide source and shuttle for antibiotic resistance

S Navon-Venezia, K Kondratyeva… - FEMS microbiology …, 2017 - academic.oup.com
Klebsiella pneumoniae is an important multidrug-resistant (MDR) pathogen affecting
humans and a major source for hospital infections associated with high morbidity and …

Novel plasmid-mediated colistin resistance gene mcr-7.1 in Klebsiella pneumoniae

YQ Yang, YX Li, CW Lei, AY Zhang… - Journal of Antimicrobial …, 2018 - academic.oup.com
Objectives To identify a novel plasmid-mediated colistin resistance gene in Klebsiella
pneumoniae isolated from chickens in China. Methods WGS was used to identify a novel …

The role of epidemic resistance plasmids and international high-risk clones in the spread of multidrug-resistant Enterobacteriaceae

AJ Mathers, G Peirano, JDD Pitout - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Escherichia coli sequence type 131 (ST131) and Klebsiella pneumoniae ST258 emerged in
the 2000s as important human pathogens, have spread extensively throughout the world …

Antibiotic resistance crisis: challenges and imperatives

NA Church, JL McKillip - Biologia, 2021 - Springer
Antibiotic resistance is one of the greatest worldwide challenges to modern medicine, and
society at large, and one of the least appreciated by practitioners and the lay community …