Nitric oxide (NO) is a gaseous molecule that has a central role in signaling pathways
involved in numerous physiological processes (eg, vasodilation, neurotransmission …

Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

Responding to tissue injury, skeletal muscles undergo the tissue destruction and
reconstruction accompanied with inflammation. The immune system recognizes the …

Skeletal muscle regeneration involves coordinated interactions between different cell types.
Injection of platelet-rich plasma is circumstantially considered an aid to muscle repair but …

Tissue-resident macrophages represent a group of highly responsive innate immune cells
that acquire diverse functions by polarizing toward distinct subpopulations. The …

Macrophages are essential players for the host response against pathogens, regulation of
inflammation and tissue regeneration. The wide range of macrophage functions rely on their …

Traumatic injuries, tumor resections, and degenerative diseases can damage skeletal
muscle and lead to functional impairment and severe disability. Skeletal muscle …

Duchenne muscular dystrophy (DMD) is a progressive disease caused by the loss of
function of the protein dystrophin. This protein contributes to the stabilisation of striated cells …

Vitamin D deficiency, prevalent worldwide, is linked to muscle weakness, sarcopenia, and
falls. Muscle regeneration is a vital process that allows for skeletal muscle tissue …

Background The skeletal muscle reconstruction occurs thanks to unipotent stem cells, ie,
satellite cells. The satellite cells remain quiescent and localized between myofiber …