Cell invasion into the surrounding extracellular matrix or across tissue boundaries and
endothelial barriers occurs in both physiological and pathological scenarios such as …

Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

Integrins are the major family of adhesion molecules that mediate cell adhesion to the
extracellular matrix. They are essential for embryonic development and influence numerous …

Biomaterial implantation is followed by an inflammatory cascade dominated by
macrophages, which determine implant acceptance or rejection through pro-and anti …

The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …

Scarring is part of the normal healing response to tissue injury in all organs and required to
rapidly repair acute damages, mostly with extracellular matrix. A variety of different cells are …

Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …

In addition to their early-recognized functions in host defense and the clearance of apoptotic
cell debris, macrophages play vital roles in tissue development, homeostasis, and repair. If …

Atherosclerosis, cancer, and various chronic fibrotic conditions are characterized by an
increase in the migratory behavior of resident cells and the enhanced invasion of assorted …

Phagocytosis is a specialized process that enables cellular ingestion and clearance of
microbes, dead cells and tissue debris that are too large for other endocytic routes. As such …