Macronutrient metabolism by the human gut microbiome: major fermentation by-products and their impact on host health

K Oliphant, E Allen-Vercoe - Microbiome, 2019 - Springer
The human gut microbiome is a critical component of digestion, breaking down complex
carbohydrates, proteins, and to a lesser extent fats that reach the lower gastrointestinal tract …

Non-alcoholic fatty liver disease as a canonical example of metabolic inflammatory-based liver disease showing a sex-specific prevalence: relevance of estrogen …

S Della Torre - Frontiers in endocrinology, 2020 - frontiersin.org
There is extensive evidence supporting the interplay between metabolism and immune
response, that have evolved in close relationship, sharing regulatory molecules and …

Meta‐analysis: prevalence of, and risk factors for, non‐alcoholic fatty liver disease in patients with inflammatory bowel disease

M Zamani, S Alizadeh‐Tabari, S Singh… - Alimentary …, 2022 - Wiley Online Library
Background Non‐alcoholic fatty liver disease (NAFLD) is found in inflammatory bowel
disease (IBD). However, uncertainties remain on the magnitude of the association. Aims To …

Probiotics-loaded nanoparticles attenuated colon inflammation, oxidative stress, and apoptosis in colitis

AG Alkushi, A Abdelfattah-Hassan, H Eldoumani… - Scientific Reports, 2022 - nature.com
Promising therapy is needed for treating inflammatory bowel diseases (IBD) to overcome
current treatment that inefficient and associated with unnecessary health risks. Recently, the …

Beyond the X factor: relevance of sex hormones in NAFLD pathophysiology

S Della Torre - Cells, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a major health issue worldwide, being
frequently associated with obesity, unbalanced dietary regimens, and reduced physical …

[HTML][HTML] Increased risk of MAFLD and liver fibrosis in inflammatory bowel disease independent of classic metabolic risk factors

JC Rodriguez-Duque, JL Calleja, P Iruzubieta… - Clinical …, 2023 - Elsevier
Background & Aims There is conflicting evidence regarding the prevalence of and risk
factors for metabolic-associated fatty liver disease (MAFLD) in patients with inflammatory …

DSS-induced colitis is associated with adipose tissue dysfunction and disrupted hepatic lipid metabolism leading to hepatosteatosis and dyslipidemia in mice

J Kwon, C Lee, S Heo, B Kim, CK Hyun - Scientific reports, 2021 - nature.com
Considering high prevalence of non-alcoholic fatty liver diseases (NAFLD) in patients with
inflammatory bowel disease (IBD), this study aimed to elucidate molecular mechanisms for …

Prevalence of nonalcoholic fatty liver disease in patients with inflammatory bowel disease: a systematic review and meta-analysis

A Lin, H Roth, A Anyane-Yeboa… - Inflammatory Bowel …, 2021 - academic.oup.com
Background Nonalcoholic fatty liver disease (NAFLD) is a significant public health burden,
with up to 30% of the US population affected. The prevalence of NAFLD among …

Gut microbiota in non-alcoholic fatty liver disease patients with inflammatory bowel diseases: a complex interplay

L Abenavoli, L Giubilei, AC Procopio, R Spagnuolo… - Nutrients, 2022 - mdpi.com
The intestinal microbiota represents the microbial community that colonizes the
gastrointestinal tract and constitutes the most complex ecosystem present in nature. The …

Ultrasound prevalence and clinical features of nonalcoholic fatty liver disease in patients with inflammatory bowel diseases: A real-life cross-sectional study

L Abenavoli, R Spagnuolo, GGM Scarlata, E Scarpellini… - Medicina, 2023 - mdpi.com
Background and Objectives: Inflammatory bowel disease (IBD) is a condition characterized
by chronic intestinal inflammation. We can identify two major forms: Crohn's disease (CD) …