The proteolytic regulation of virus cell entry by furin and other proprotein convertases

G Izaguirre - Viruses, 2019 - mdpi.com
A wide variety of viruses exploit furin and other proprotein convertases (PCs) of the
constitutive protein secretion pathway in order to regulate their cell entry mechanism and …

Immunological tolerance of low-risk HPV in recurrent respiratory papillomatosis

R Ivancic, H Iqbal, B Desilva, Q Pan… - Clinical & Experimental …, 2020 - academic.oup.com
Recurrent respiratory papillomatosis (RRP) is characterized by benign exophytic lesions of
the respiratory tract caused by the human papillomavirus (HPV), in particular low-risk HPV6 …

Soil bacterial and fungal communities and the associated nutrient cycling responses to forest conversion after selective logging in a subtropical forest of China

X Jin, Y Liu, W Hu, G Wang, Z Kong, L Wu… - Forest Ecology and …, 2019 - Elsevier
Forest conversion can affect the diversity and community structure of soil bacteria and fungi.
However, little is known about the impact of forest conversion on aboveground-belowground …

Altered monocyte and langerhans cell innate immunity in patients with recurrent respiratory papillomatosis (RRP)

M Israr, JA DeVoti, F Lam, AL Abramson… - Frontiers in …, 2020 - frontiersin.org
The micromilieu within respiratory papillomas supports persistent human papillomavirus
(HPV) infection and disease recurrence in patients with recurrent respiratory papillomatosis …

Combined transcriptome and proteome analysis of immortalized human keratinocytes expressing human papillomavirus 16 (HPV16) oncogenes reveals novel key …

R Yang, J Klimentová, E Göckel-Krzikalla, R Ly… - Msphere, 2019 - Am Soc Microbiol
Although the role of high-risk human papillomaviruses (hrHPVs) as etiological agents in
cancer development has been intensively studied during the last decades, there is still the …

Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions

K Campos-León, J Ferguson, T Günther… - PLoS …, 2025 - journals.plos.org
Upon infection, human papillomavirus (HPV) manipulates host cell gene expression to
create an environment that is supportive of a productive and persistent infection. The virus …

Extracellular vesicles produced by primary human keratinocytes in response to TLR agonists induce stimulus-specific responses in antigen-presenting cells

CJ Papayannakos, JA DeVoti, M Israr, H Alsudani… - Cellular signalling, 2021 - Elsevier
Cells can communicate through the extracellular vesicles (EVs) they secrete. Pathogen
associated molecular patterns (PAMPs), alter the biophysical and communicative properties …

Oral host-microbe interactions investigated in 3D organotypic models

L Shang, D Deng, BP Krom, S Gibbs - Critical reviews in …, 2024 - Taylor & Francis
The oral cavity is inhabited by abundant microbes which continuously interact with the host
and influence the host's health. Such host-microbe interactions (HMI) are dynamic and …

[HTML][HTML] Dysregulation of FURIN and Other Proprotein Convertase Genes in the Progression from HPV Infection to Cancer

G Izaguirre, N Zirou, C Meyers - International Journal of Molecular …, 2025 - mdpi.com
Productive infections of oncogenic human papillomaviruses (HPVs) are closely linked to the
differentiation of host epithelial cells, a process that the virus manipulates to create …

Diversity in Proprotein Convertase Reactivity among Human Papillomavirus Types

G Izaguirre, LMU Phan, S Asif, S Alam, C Meyers… - Viruses, 2023 - mdpi.com
The cleavage of viral surface proteins by furin is associated with some viruses' high
virulence and infectivity. The human papillomavirus (HPV) requires the proteolytic …