NF-κB signaling in gastric cancer

O Sokolova, M Naumann - Toxins, 2017 - mdpi.com
Gastric cancer is a leading cause of cancer death worldwide. Diet, obesity, smoking and
chronic infections, especially with Helicobacter pylori, contribute to stomach cancer …

[HTML][HTML] Phytochemicals targeting NF-κB signaling: Potential anti-cancer interventions

A Chauhan, AU Islam, H Prakash, S Singh - Journal of pharmaceutical …, 2022 - Elsevier
Nuclear factor κB (NF-κB) is a ubiquitous regulator of the signalome and is indispensable for
various biological cell functions. NF-κB consists of five transcription factors that execute both …

[HTML][HTML] Overview on the role of E-cadherin in gastric cancer: dysregulation and clinical implications

H Zhao, H Hu, B Chen, W Xu, J Zhao… - Frontiers in Molecular …, 2021 - frontiersin.org
Gastric cancer is the fifth most common cancer and the third most common cause of cancer
death all over the world. E-cadherin encoded by human CDH1 gene plays important roles in …

Interaction between Wnt/β-catenin pathway and microRNAs regulates epithelial-mesenchymal transition in gastric cancer

C Wu, Y Zhuang, S Jiang, S Liu… - International …, 2016 - spandidos-publications.com
Gastric cancer (GC) is the third primary cause of cancer-related mortality and one of the most
common type of malignant diseases worldwide. Despite remarkable progress in …

From cell membrane to the nucleus: An emerging role of E‐cadherin in gene transcriptional regulation

W Du, X Liu, G Fan, X Zhao, Y Sun… - Journal of cellular …, 2014 - Wiley Online Library
E‐cadherin is a well‐known mediator of cell–cell adherens junctions. However, many other
functions of E‐cadherin have been reported. Collectively, the available data suggest that E …

NF-κB in gastric cancer development and therapy

S Chaithongyot, P Jantaree, O Sokolova, M Naumann - Biomedicines, 2021 - mdpi.com
Gastric cancer is considered one of the most common causes of cancer-related death
worldwide and, thus, a major health problem. A variety of environmental factors including …

Sufentanil Inhibits the Proliferation and Metastasis of Esophageal Cancer by Inhibiting the NF‐κB and Snail Signaling Pathways

H Tang, C Li, Y Wang, L Deng - Journal of oncology, 2021 - Wiley Online Library
Sufentanil is a μ‐opioid receptor agonist, widely used in intraoperative and postoperative
analgesia of esophageal cancer. This study investigated the effects of sufentanil on the …

COX-2 regulates E-cadherin expression through the NF-κB/Snail signaling pathway in gastric cancer Corrigendum in/10.3892/ijmm. 2022.5083

Z Chen, MIN Liu, X Liu, S Huang… - International …, 2013 - spandidos-publications.com
Abstract Cyclooxygenase-2 (COX-2) participates in cancer invasion and metastasis by
decreasing the expression of E-cadherin. However, the molecular mechanisms through …

Effects of Qingshen granules on the oxidative stress‐NF/kB signal pathway in unilateral ureteral obstruction rats

H Jin, Y Wang, D Wang, L Zhang - … ‐Based Complementary and …, 2018 - Wiley Online Library
Background. The activation of NF‐kappa B (NF/kB) signaling pathway plays an important
role in the process of epithelial‐mesenchymal transition (EMT) and renal interstitial fibrosis …

Effects and mechanisms of saikosaponin D improving the sensitivity of human gastric cancer cells to cisplatin

J Hu, P Li, B Shi, J Tie - ACS omega, 2021 - ACS Publications
Gastric cancer (GC) is the second leading cause of cancer deaths around the world.
Chemoresistance is an important reason for poor prognosis of GC. Saikosaponin D (SSD) is …