CC chemokines (or β-chemokines) are 28 chemotactic cytokines with an N-terminal CC
domain that play an important role in immune system cells, such as CD4+ and CD8+ …

Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the causal factor in
over 99% of cervical cancer cases, and a significant proportion of oropharyngeal and …

A majority of human papillomavirus (HPV) infections are asymptomatic and self-resolving in
the absence of medical interventions. Various innate and adaptive immune responses, as …

Chemokines and their receptors play an important role in the recruitment, activation and
differentiation of immune cells. The chemokine receptor, CXCR3, and its ligands, CXCL9 …

The characteristics of the tumour cells, as well as how tumour cells interact with their
surroundings, affect the prognosis of cancer patients. The resident cells in the tumour …

Mast cells (MCs) are tissue-resident immune cells that are important players in diseases
associated with chronic inflammation such as cancer. Since MCs can infiltrate solid tumors …

Communication between cancer cells and their microenvironment plays an important role in
cancer development, but the precise mechanisms by which cancer-associated fibroblasts …

Retinoic acid-inducible gene I (RIG-I) is a key pattern recognition receptor that senses viral
RNA and interacts with the mitochondrial adaptor MAVS, triggering a signaling cascade that …

IgE is the least abundant circulating antibody class but is constitutively present in healthy
tissues bound to resident cells via its high-affinity receptor, FcεRI. The physiological role of …

The growth of human papillomavirus (HPV)-transformed cells depends on the ability of the
viral oncoproteins E6 and E7, especially those from high-risk HPV16/18, to manipulate the …