Univariate and multivariate determination of dapagliflozin and saxagliptin in bulk and dosage form

MM Elhassan, AM Mahmoud… - Journal of AOAC …, 2023 - academic.oup.com
Background Dapagliflozin is a sodium glucose cotransporter-II inhibitor while saxagliptin is a
dipeptidyl peptidase-4 inhibitor. Both are used to manage type 2 diabetes mellitus. Objective …

Application of quality-by-design for adopting an environmentally green fluorogenic determination of benoxinate hydrochloride in eye drops and artificial aqueous …

MA El Hamd, M El-Maghrabey, G Magdy, WA Mahdi… - Scientific Reports, 2023 - nature.com
Herein, a sensitive and selective spectrofluorimetric method has been developed for the
determination of the ocular local anesthetic benoxinate hydrochloride (BEN-HCl) in eye …

Use of Chemical Reagents in Non-fluorescent Pharmaceutical Labels: A Comprehensive Review

BK Devi, K Madhavi, S Naraparaju… - Current …, 2023 - ingentaconnect.com
Spectrofluorimetry is an analytical technique with high sensitivity, specificity, and simplicity,
and is very economical. Drugs that lack native fluorescence are derivatized with reagents so …

Synthesis of Cysteine Modified MoS2 Nanocomposite: A Biocompatible Electrochemical Sensor Material and its Application to the Determination of Antidiabetic …

AK Ateş, H Çelikkan, N Erk - Electroanalysis, 2020 - Wiley Online Library
Herein, for the first time, a new generation cysteine modified MoS2 (Cys@ MoS2) based
electrochemical sensor was reported. The electrochemical behaviour of dapagliflozin (DAP) …

HPTLC-densitometric analysis of selected antidiabetic drugs in presence of their degradation products

HM Ahmed, MA Omar, HA Batakoushy… - Microchemical Journal, 2020 - Elsevier
In recent years, a lot of single-pill combinations (SPC) manufactured and are used as a
promising choice in diabetes treatment. However, this trend made a serious challenge to …

Integrated approach of white analytical chemistry and design of experiments to microwave-assisted sensitive and eco-friendly spectrofluorimetric estimation of …

P Prajapati, K Patel, A Patel, VS Pulusu… - … Acta Part A: Molecular …, 2024 - Elsevier
The USFDA recently approved mirabegron, a novel once-daily β-3 adrenoceptor agonist for
oral administration, as a transformative treatment for overactive bladder. Despite the …

Dual benefits of NBD‐Cl fluorogenic action and sample pretreatment (SALLE) technology in the assessment of anticoagulant medication: Dabigatran in …

MA El Hamd, WA Mahdi, S Alshehri… - …, 2024 - Wiley Online Library
Dabigatran (DBG), marketed as Pradaxa, is an anticoagulant medication prescribed for the
treatment and mitigation of blood clots and to lower the risk of stroke in individuals with the …

Whiteness and greenness assessments of a sensitive HPLC method with fluorimetric detection for dapagliflozin quantitation in human plasma: Application to a healthy …

MR Habeeb, SM Morshedy, HG Daabees… - Archiv der …, 2024 - Wiley Online Library
The evident ecological impact of human actions, like air pollution, global warming, and
ozone depletion, underscores the need for environmentally friendly approaches across …

A Turn-On–Type Fluorescence Resonance Energy Transfer Eco-friendly Method for Nitazoxanide Quantification in Pharmaceutical Dosage Form and Spiked Plasma …

EA Mostafa, EF Elkady, MA El-Didamoony… - Journal of …, 2023 - Springer
A brand-new class of anti-infective drugs that work against bacteria, viruses, and protozoan
parasites is nitazoxanide and related thiazolides. Thiazolides have also been shown to …

A novel high throughput 96‐well‐based fluorimetric method to measure amikacin in pharmaceutical formulations: development using response surface methodology

A Maxwell, E Mary, V Ghate, J Aranjani… - Luminescence, 2022 - Wiley Online Library
An aminoglycoside antibiotic, amikacin, is used to treat severe and recurring bacterial
infections. Due to the absence of a chromophore, however, amikacin must be extensively …