With some indoles and azaindoles being successfully developed as anticancer drugs, the
design and synthesis of indole and azaindole derivatives with remarkable antitumor activity …

The rise and spread of antimicrobial resistance represents one of the most pressing health
issues of today. Antimicrobial resistance in micro-organisms can arise due to a multiplicity of …

Quinazolinones are common substructures in molecules of medicinal importance. We report
an enantioselective copper‐catalyzed borylative cyclization for the assembly of privileged …

Malaria, leishmaniasis, and sleeping sickness are potentially fatal diseases that represent a
real health risk for more than 3, 5 billion people. New antiparasitic compounds are urgent …

Background: Urena sinuata L. is a shrubby wild plant used for centuries in folk medicine to
treat bronchitis, rheumatism, fever, and waist pain. It is evident that it possesses antioxidant …

Pirfenidone, an antifibrotic drug, has antitumor potential against different types of cancers.
Our work explored whether pirfenidone sensitizes non-small cell lung cancer (NSCLC) cell …

Ginkgo tea is a kind of health food produced from Ginkgo biloba leaves. The market of
Ginkgo tea encountered many difficulties because of its bad palatability and vague function …

Pruritus, the most common symptom in dermatology, is an innate response capable of
protecting skin against irritants. Nonetheless, when it lasts more than six weeks it is …

Neurodegenerative diseases (ND) share common molecular/cellular mechanisms that
contribute to their progression and pathogenesis. In this sense, we are here proposing new …

A series of novel functionalized methyl 3-(hetero) arylthieno [3, 2-b] pyridine-2-carboxylates
2a–2h were synthesized by CC Pd-catalyzed Suzuki-Miyaura cross-coupling of methyl 3 …