Production of secondary metabolites using tissue culture-based biotechnological applications

II Ozyigit, I Dogan, A Hocaoglu-Ozyigit… - Frontiers in Plant …, 2023 - frontiersin.org
Plants are the sources of many bioactive secondary metabolites which are present in plant
organs including leaves, stems, roots, and flowers. Although they provide advantages to the …

Euphorbia diterpenoids: isolation, structure, bioactivity, biosynthesis, and synthesis (2013–2021)

Z Zhan, S Li, W Chu, S Yin - Natural Product Reports, 2022 - pubs.rsc.org
Covering: 2013 to 2021 As the characteristic metabolites of Euphorbia plants, Euphorbia
diterpenoids have always been a hot topic in related science communities due to their …

Plant terpene specialized metabolism: complex networks or simple linear pathways?

ER Lanier, TB Andersen, B Hamberger - The Plant Journal, 2023 - Wiley Online Library
From the perspectives of pathway evolution, discovery and engineering of plant specialized
metabolism, the nature of the biosynthetic routes represents a critical aspect. Classical …

[HTML][HTML] Key oncologic pathways inhibited by Erinacine A: a perspective for its development as an anticancer molecule

P Prasher, M Sharma, AK Sharma, J Sharifi-Rad… - Biomedicine & …, 2023 - Elsevier
In the modern era, cancer can be controlled by chemotherapy treatment, and in many
situations a stable disease is obtained. The significant clinical success and subsequent …

Yuexiandajisu diterpenoids from Euphorbia ebracteolata Hayata (Langdu roots): An overview

C Bailly - Phytochemistry, 2023 - Elsevier
The roots of the plant Euphorbia ebracteolata Hayata (Yue Xian Da Ji) are commonly used
in traditional Chinese medicine to treat multiple diseases such as chronic liver diseases …

Myrsinane-type diterpenes: A comprehensive review on structural diversity, chemistry and biological activities

E Mendes, C Ramalhete, N Duarte - International Journal of Molecular …, 2023 - mdpi.com
Euphorbia species are important sources of polycyclic and macrocyclic diterpenes, which
have been the focus of natural-product-based drug research due to their relevant biological …

Nature's green potential: Anticancer properties of plants of the Euphorbiaceae family

V Jiménez-González, T Kowalczyk, J Piekarski… - Cancers, 2023 - mdpi.com
Simple Summary Euphorbiaceae is a large family of flowering plants that includes a wide
spectrum of useful plants, from edible plants to toxic and medicinal plants. They are …

Diterpenoids with Rearranged 9(10→11)-abeo-10,12-Cyclojatrophane Skeleton and the First (15S)-Jatrophane from Euphorbia helioscopia: Structural Elucidation …

ZN Xiang, QL Tong, JC Su, ZF Hu, N Zhao, RF Xia… - Organic …, 2021 - ACS Publications
Two novel diterpenoids, one with a rearranged trans, trans-fused tricyclo [10.3. 0.04, 6]
pentadecane framework (1) and the other with an unprecedented 15 S configuration (2) …

LC-QToF chemical profiling of Euphorbia grantii Oliv. and its potential to inhibit LPS-induced lung inflammation in rats via the NF-κB, CY450P2E1, and P38 MAPK14 …

MH Radi, RA El-Shiekh, AM Hegab, SR Henry… - …, 2024 - Springer
Acute lung injury (ALI) is a life-threatening syndrome that causes high morbidity and
mortality worldwide. The aerial parts of Euphorbia grantii Oliv. were extracted with methanol …

The role of ingenane diterpenes in cancer therapy: From bioactive secondary compounds to small molecules

ALV Alves, LS da Silva, CA Faleiros… - Natural Product …, 2022 - journals.sagepub.com
Diterpenes are a class of critical taxonomic markers of the Euphorbiaceae family,
representing small compounds (eg, molecules) with a wide range of biological activities and …