The cells in the human body are continuously challenged by a variety of genotoxic attacks.
Erroneous repair of the DNA can lead to mutations and chromosomal aberrations that can …

Colorectal cancer (CRC) is the third leading cause of cancer death worldwide, which is
consequence of multistep tumorigenesis of several genetic and epigenetic events. Since …

A common feature of aging is the accumulation of genetic damage throughout life. DNA
damage can lead to genomic instability. Many diseases associated with premature aging …

Hairdressers are exposed to high levels of chemicals, including possible carcinogens. For
dermal exposure, the skin protects against the uptake of chemicals and the protein filaggrin …

Mismatch repair (MMR) genes play an important role in the occurrence and development of
sporadic colorectal cancer; however, the effect of MMR genes on clinicopathological …

Telomere biology is central to the maintenance of genomic stability and telomeric
dysfunction is thought to be an early stage in carcinogenesis. Reports of telomere lengths …

Context Colorectal cancer is one of the most common cancers worldwide (the third most
common cancer in the world) and is especially more common in Western countries; …

Gout is the most common auto-inflammatory arthritis that leads to severe comorbidities such
as cardiovascular diseases, renal impairment and metabolic disorders at an early age. We …

El desarrollo de sistemas transportadores de fármacos ha alcanzado en Biomedicina un
papel muy importante, concretamente en la terapia de enfermedades severas como el …

La disfunción telomérica constituye un evento frecuente en el cáncer colorrectal (CCR). El
objetivo de este trabajo consiste en analizar el estatus telomérico y las sirtuinas 1 y 6, en …