Atherosclerosis, a chronic inflammatory condition, remains a leading cause of death globally, necessitating innovative approaches to target pro-atherogenic pathways. Recent …
S Li, Y Cao, X Cui, J Sun - Aquaculture, 2024 - Elsevier
Abstract Aconitate decarboxylase 1 (ACOD1, formerly termed as immunoresponsive gene 1) is an enzyme responsible for generation of anti-inflammatory metabolite itaconate through …
ME Mickael, N Kubick, AG Atansov, JO Horbańczuk… - 2024 - preprints.org
Sepsis is a serious disease that can lead to mortality. The etiology of the disease is connected to how the body as a host reacts toward microbes such as bacteria, viruses, and …
J Xu, S Xu - Trends in Molecular Medicine, 2024 - cell.com
As an endogenous immunometabolite, itaconate has excellent anti-inflammatory effects. However, it remains unknown whether itaconate protects against atherosclerosis. Two …