Background & Aims Cholangiocarcinoma (CCA) carries a poor prognosis, is increasing in
incidence and its causes are poorly understood. Although some risk factors are known, they …

Cholangiocarcinoma (CCA) is the second most common primary malignancy. Although it is
more common in Asia, its incidence in Europe and North America has significantly increased …

Gut dysbiosis is commonly observed in patients with cirrhosis and chronic gastrointestinal
disorders; however, its effect on antitumor immunity in the liver is largely unknown. Here we …

Primary liver cancer represents a major health problem. It comprises hepatocellular
carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), which differ markedly with …

Background Intrahepatic cholangiocarcinomas (ICCs) and extrahepatic
cholangiocarcinomas (ECCs) are highly lethal bile duct tumors. Their incidence can be …

Cholangiocarcinoma (CCA) comprises a heterogeneous group of cancers with pathologic
features of biliary tract differentiation, and is presumed to arise from the intra-or extrahepatic …

Objectives To summarise the evidence and evaluate the validity of the associations between
type 2 diabetes and the risk of developing or dying from cancer. Design An umbrella review …

Cholangiocarcinoma represents a diverse group of epithelial cancers united by late
diagnosis and poor outcomes. Specific diagnostic and therapeutic approaches are …

Background Cholangiocarcinomas are a heterogeneous group of malignancies arising from
a number of cells of origin along the biliary tree. Although most cases in Western countries …

Chronic HCV infection is a global health problem that affects> 184 million people worldwide.
HCV is associated with several hepatic and extrahepatic disorders, including several …