Indole-Containing Phytoalexin-Based Bioisosteres as Antifungals: In Vitro and In Silico Evaluation against Fusarium oxysporum

A Angarita-Rodríguez, D Quiroga, E Coy-Barrera - Molecules, 2019 - mdpi.com
There is a continuous search for more reliable and effective alternatives to control
phytopathogens through different strategies. In this context, indole-containing phytoalexins …

Discrimination of naturally-occurring 2-arylbenzofurans as cyclooxygenase-2 inhibitors: Insights into the binding mode and enzymatic inhibitory activity

E Coy-Barrera - Biomolecules, 2020 - mdpi.com
2-arylbenzofuran-containing compounds are chemical entities that can be naturally
produced by several organisms. A wide-range of activities is described for several …

Towards an understanding of the mode of action of human aromatase activity for azoles through quantum chemical descriptors-based regression and structure activity …

C Chayawan, C Toma, E Benfenati… - Molecules, 2020 - mdpi.com
Aromatase is an enzyme member of the cytochrome P450 superfamily coded by the
CYP19A1 gene. Its main action is the conversion of androgens into estrogens, transforming …