Inflammaging and osteoarthritis

F Motta, E Barone, A Sica, C Selmi - Clinical Reviews in Allergy & …, 2023 - Springer
Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age
worldwide. While in the past it was considered a mere consequence of cartilage degradation …

Epidemiology of osteoarthritis: literature update

ER Vina, CK Kwoh - Current opinion in rheumatology, 2018 - journals.lww.com
Epidemiology of osteoarthritis: literature update : Current Opinion in Rheumatology
Epidemiology of osteoarthritis: literature update : Current Opinion in Rheumatology Log in or …

Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis

CH Chou, V Jain, J Gibson, DE Attarian… - Scientific Reports, 2020 - nature.com
We elucidated the molecular cross-talk between cartilage and synovium in osteoarthritis, the
most widespread arthritis in the world, using the powerful tool of single-cell RNA …

Hyperglycemia-induced accumulation of advanced glycosylation end products in fibroblast-like synoviocytes promotes knee osteoarthritis

Q Li, Y Wen, L Wang, B Chen, J Chen… - … & Molecular Medicine, 2021 - nature.com
Osteoarthritis (OA) is significantly associated with diabetes, but how hyperglycemia induces
or aggravates OA has not been shown. The synovium plays a critical role in cartilage …

Chondroitin sulfate microspheres anchored with drug-loaded liposomes play a dual antioxidant role in the treatment of osteoarthritis

Y He, M Sun, J Wang, X Yang, C Lin, L Ge, C Ying… - Acta Biomaterialia, 2022 - Elsevier
Reactive oxygen species (ROS) play a critical role in the pathogenesis of osteoarthritis. The
injection of a single antioxidant drug is characterized by low drug utilization and short …

Exosomes and stem cells in degenerative disease diagnosis and therapy

YH Chang, KC Wu, HJ Harn, SZ Lin… - Cell …, 2018 - journals.sagepub.com
Stroke can cause death and disability, resulting in a huge burden on society. Parkinson's
disease (PD) is a chronic neurodegenerative disorder characterized by motor dysfunction …

[HTML][HTML] Clinical, humanistic, and economic burden of osteoarthritis among noninstitutionalized adults in the United States

X Zhao, D Shah, K Gandhi, W Wei, N Dwibedi… - Osteoarthritis and …, 2019 - Elsevier
Objective To estimate the burden of osteoarthritis (OA) among noninstitutionalized adults (≥
18 years of age) in the US. Design Weighted nationally representative data from the 2015 …

Quality of life assessment in musculo-skeletal health

C Beaudart, E Biver, O Bruyère, C Cooper… - Aging clinical and …, 2018 - Springer
Musculoskeletal disorders affect morbidity, quality of life and mortality, and represent an
increasing economic and societal burden in the context of population aging and increased …

A review on segmentation of knee articular cartilage: from conventional methods towards deep learning

S Ebrahimkhani, MH Jaward, FM Cicuttini… - Artificial intelligence in …, 2020 - Elsevier
In this paper, we review the state-of-the-art approaches for knee articular cartilage
segmentation from conventional techniques to deep learning (DL) based techniques. Knee …

Core and adjunctive interventions for osteoarthritis: efficacy and models for implementation

JL Bowden, DJ Hunter, LA Deveza, V Duong… - Nature Reviews …, 2020 - nature.com
Osteoarthritis (OA) is a complex musculoskeletal disease and a leading cause of pain and
disability worldwide. Hip and knee OA alone are major contributors to global disability …