Early detection of cancer
Survival improves when cancer is detected early. However,~ 50% of cancers are at an
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …
Synthetic biomarkers: a twenty-first century path to early cancer detection
Detection of cancer at an early stage when it is still localized improves patient response to
medical interventions for most cancer types. The success of screening tools such as cervical …
medical interventions for most cancer types. The success of screening tools such as cervical …
Wearable materials with embedded synthetic biology sensors for biomolecule detection
Integrating synthetic biology into wearables could expand opportunities for noninvasive
monitoring of physiological status, disease states and exposure to pathogens or toxins …
monitoring of physiological status, disease states and exposure to pathogens or toxins …
Cell-free biosensors for rapid detection of water contaminants
Lack of access to safe drinking water is a global problem, and methods to reliably and easily
detect contaminants could be transformative. We report the development of a cell-free in …
detect contaminants could be transformative. We report the development of a cell-free in …
Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson's disease treatment
Exosomes are cell-derived nanovesicles (50–150 nm), which mediate intercellular
communication, and are candidate therapeutic agents. However, inefficiency of exosomal …
communication, and are candidate therapeutic agents. However, inefficiency of exosomal …
An ingestible bacterial-electronic system to monitor gastrointestinal health
Biomolecular monitoring in the gastrointestinal tract could offer rapid, precise disease
detection and management but is impeded by access to the remote and complex …
detection and management but is impeded by access to the remote and complex …
[HTML][HTML] Rapid, low-cost detection of Zika virus using programmable biomolecular components
The recent Zika virus outbreak highlights the need for low-cost diagnostics that can be
rapidly developed for distribution and use in pandemic regions. Here, we report a pipeline …
rapidly developed for distribution and use in pandemic regions. Here, we report a pipeline …
Engineering customized cell sensing and response behaviors using synthetic notch receptors
The Notch protein is one of the most mechanistically direct transmembrane receptors—the
intracellular domain contains a transcriptional regulator that is released from the membrane …
intracellular domain contains a transcriptional regulator that is released from the membrane …
Neural network detection of data sequences in communication systems
N Farsad, A Goldsmith - IEEE Transactions on Signal …, 2018 - ieeexplore.ieee.org
We consider detection based on deep learning, and show it is possible to train detectors that
perform well without any knowledge of the underlying channel models. Moreover, when the …
perform well without any knowledge of the underlying channel models. Moreover, when the …
Point-of-care diagnostics: recent developments in a connected age
S Nayak, NR Blumenfeld, T Laksanasopin… - Analytical …, 2017 - ACS Publications
The field of point-of-care (POC) diagnostics offers the tantalizing possibility of providing
rapid diagnostic results in nonlaboratory settings. Here, we review progress in this research …
rapid diagnostic results in nonlaboratory settings. Here, we review progress in this research …