While the intranasal administration of drugs to the brain has been gaining both research attention and regulatory success over the past several years, key fundamental and …
R Taliyan, V Kakoty, KC Sarathlal… - Journal of Controlled …, 2022 - Elsevier
For the past several years, dementia, is one of the predominantly observed groups of symptoms in a geriatric population. Alzheimer's disease (AD) is a progressive memory …
This work focuses on developing nanoemulsions using a low-energy emulsification method for the codelivery of donepezil and memantine in one dosage form intended to be …
M Soni, M Handa, KK Singh, R Shukla - Journal of Controlled Release, 2022 - Elsevier
COVID-19 acquired symptoms have affected the worldwide population and increased the load of Intensive care unit (ICU) patient admissions. A large number of patients admitted to …
M Handa, S Beg, R Shukla, MA Barkat… - Journal of Controlled …, 2021 - Elsevier
Cancer is a leading cause of death in many countries around the world. However, the efficacy of current treatments available for variety of cancers is considered to be suboptimal …
Dementia, most often associated with neurodegenerative diseases, affects millions of people worldwide, predominantly the elderly. Unfortunately, no treatment is still available …
(1) Background: Thymus vulgaris L.(thyme) essential oil (TEO) has gained much attention because of its long history of medicinal usage. However, the lack of precise chemical …
E Santamaría, A Maestro, S Vilchez, C González - Heliyon, 2023 - cell.com
Carvacrol is studied in different fields due to its microbial and antioxidant properties. Its use is limited because of the water insolubility and its strong taste. To overcome these problems …
PC Pires, AC Paiva-Santos, F Veiga - Pharmaceutics, 2022 - mdpi.com
Most drugs used for the treatment of depression, anxiety and related disorders have low absorption, high metabolism, low brain targeting and/or low water solubility, which can make …