Anti-amyloid antibody therapies in Alzheimer's disease

R Perneczky, F Jessen, T Grimmer, J Levin, A Flöel… - Brain, 2023 - academic.oup.com
After years of failed attempts to develop a disease-modifying therapy for Alzheimer's
disease, consistent evidence in support of clinical efficacy was finally presented for a …

Identifying modifiable factors and their joint effect on dementia risk in the UK Biobank

Y Zhang, SD Chen, YT Deng, J You, XY He… - Nature human …, 2023 - nature.com
Previous hypothesis-driven research has identified many risk factors linked to dementia.
However, the multiplicity and co-occurrence of risk factors have been underestimated. Here …

Global biomarker trends in Alzheimer's research: a bibliometric analysis

K Noda, Y Lim, S Sengoku, K Kodama - Drug Discovery Today, 2023 - Elsevier
Alzheimer's disease (AD) has no effective treatment, although antibody drugs targeting beta-
amyloid, mainly aducanumab, have produced useful clinical results. Biomarkers can be …

Association between coffee and tea consumption and the risk of dementia in individuals with hypertension: a prospective cohort study

B Wang, T Ma, L Yang, S He, J Li, X Sun - Scientific Reports, 2024 - nature.com
Many studies have shown that drinking coffee and tea may be associated with the risk of
hypertension and dementia. Limited research exists on their impact on dementia risk in …

Socioeconomic status, lifestyle and risk of incident dementia: a prospective cohort study of 276730 participants

YN Ou, YB Zhang, YZ Li, SY Huang, W Zhang… - Geroscience, 2024 - Springer
Healthy lifestyle might alleviate the socioeconomic inequities in health, but the extent of the
joint and interactive effects of these two factors on dementia are unclear. This study aimed to …

[HTML][HTML] Mobility-Based Smartphone Digital Phenotypes for Unobtrusively Capturing Everyday Cognition, Mood, and Community Life-Space in Older Adults: Feasibility …

K Hackett, S Xu, M McKniff, L Paglia… - JMIR Human …, 2024 - humanfactors.jmir.org
Background Current methods of monitoring cognition in older adults are insufficient to
address the growing burden of Alzheimer disease and related dementias (AD/ADRD). New …

Attitudes and Preferences Towards Screening for Dementia with a Focus on Ethnic Minority and Low Socio-Economic Groups: A Systematic Review of Research …

M Brar, R Mc Ardle, A Hagan… - Journal of …, 2024 - journals.sagepub.com
Background: Increased understanding of dementia risk-reduction and early detection of
Alzheimer's disease and related disorders has spurred interest in the identification of risks …

The likelihood of hospital‐acquired complications in older people with dementia: a matched cohort study

DN Chróinín, V Deane… - Medical Journal of …, 2024 - Wiley Online Library
Objectives To investigate whether the likelihood of hospital‐acquired complications for older
people in Australia differs by whether they have dementia. Study design Matched cohort …

Implementing new dementia care models in practice

VK Ramanan - CONTINUUM: Lifelong Learning in Neurology, 2024 - journals.lww.com
Care for patients with Alzheimer disease and related neurodegenerative causes of dementia
is in the midst of a transformation. Recent advancements in diagnostics and therapeutics …

[HTML][HTML] The deprivation cascade hypothesis of dementia

T Daly - Aging and Health Research, 2024 - Elsevier
There are significant disparities in dementia risk and care burden in the global population.
This review provides evidence of the effects of deprivation, understood as the absence of …