Inhalable particulate drug delivery systems for lung cancer therapy: Nanoparticles, microparticles, nanocomposites and nanoaggregates

HM Abdelaziz, M Gaber, MM Abd-Elwakil… - Journal of Controlled …, 2018 - Elsevier
There is progressive evolution in the use of inhalable drug delivery systems (DDSs) for lung
cancer therapy. The inhalation route offers many advantages, being non-invasive method of …

Recent advances in the development of multifunctional lipid-based nanoparticles for co-delivery, combination treatment strategies, and theranostics in breast and lung …

YS Loo, NI Zahid, T Madheswaran, IDM Azmi - Journal of Drug Delivery …, 2022 - Elsevier
Cancer nanomedicines and the development of state-of-the-art multifunctional lipid-based
nanoparticles (NPs) has become a fundamental resource in resolving challenging …

Self-assembled amphiphilic zein-lactoferrin micelles for tumor targeted co-delivery of rapamycin and wogonin to breast cancer

SA Sabra, AO Elzoghby, SA Sheweita… - European Journal of …, 2018 - Elsevier
Protein-based micelles have shown significant potential for tumor-targeted delivery of anti-
cancer drugs. In this light, self-assembled nanocarriers based on GRAS (Generally …

Synthesis of lactoferrin mesoporous silica nanoparticles for pemetrexed/ellagic acid synergistic breast cancer therapy

OM Ali, AA Bekhit, SN Khattab, MW Helmy… - Colloids and Surfaces B …, 2020 - Elsevier
Despite the clinical approval of few nanomedicines for cancer therapy, some drawbacks still
impede their improved efficiency including low drug loading, off-target toxicity and …

Folic acid receptor-targeted solid lipid nanoparticles to enhance cytotoxicity of letrozole through induction of caspase-3 dependent-apoptosis for breast cancer …

A Yassemi, S Kashanian, H Zhaleh - … development and technology, 2020 - Taylor & Francis
Chemotherapy using cytotoxic agents, such as letrozole (LTZ), is one of the most effective
treatments for hormone-dependent breast cancer. Nevertheless, nonspecific targeting of the …

[HTML][HTML] Co-delivery of letrozole and cyclophosphamide via folic acid-decorated nanoniosomes for breast cancer therapy: synergic effect, augmentation of cytotoxicity …

H Sahrayi, E Hosseini, S Karimifard, N Khayam… - Pharmaceuticals, 2021 - mdpi.com
Breast cancer is one of the most prevalent causes of cancer mortality in women. In order to
increase patient prognosis and survival rates, new technologies are urgently required to …

Chondroitin/Lactoferrin-dual functionalized pterostilbene-solid lipid nanoparticles as targeted breast cancer therapy

S Aly, AH El-Kamel, E Sheta, SE El-Habashy - International Journal of …, 2023 - Elsevier
Breast cancer remains the leading cause of cancer-associated mortality in women.
Research investigating novel therapeutic approaches is thus crucial, including …

Inhalable lactoferrin–chondroitin nanocomposites for combined delivery of doxorubicin and ellagic acid to lung carcinoma

MM Abd Elwakil, MT Mabrouk, MW Helmy… - …, 2018 - Taylor & Francis
Aim: The use of inhalable nanomedicines can overcome the Enhanced permeation and
retention effect (EPR)-associated drawbacks in lung cancer therapy via systemic …

[HTML][HTML] Surface modified genistein phytosome for breast cancer treatment: In-vitro appraisal, pharmacokinetics, and in-vivo antitumor efficacy

IA Komeil, OY Abdallah, WM El-Refaie - European Journal of …, 2022 - Elsevier
Based on phytosomes advantages over liposomes, hyaluronic acid (HA) with/out pegylated
phospholipid was used to develop surface-modified genistein (Gen) phytosome as Gen …

Lactoferrin-tagged quantum dots-based theranostic nanocapsules for combined COX-2 inhibitor/herbal therapy of breast cancer

AS AbdElhamid, DG Zayed, MW Helmy… - …, 2018 - Taylor & Francis
Aim: Herein, tumor-targeted quantum dots (QDs)-based theranostic nanocapsules (NCs)
coloaded with celecoxib and honokiol were developed. Materials & methodology: The …