Exploring 1, 2, 3-triazole-Schiff's base hybrids as innovative EGFR inhibitors for the treatment of breast cancer: In vitro and in silico study
NA Nawareg, ASA Yassen, EM Husseiny… - Bioorganic …, 2025 - Elsevier
EGFR inhibitors are a class of targeted therapies utilized in the management of certain tumor
kinds such as NSCLC and breast cancer. Series of 1, 2, 3-triazole-Schiff's base hybrids were …
kinds such as NSCLC and breast cancer. Series of 1, 2, 3-triazole-Schiff's base hybrids were …
Novel flavonoid derivatives containing 1, 2, 4-triazole Schiff bases as potential antifungal agents: design, synthesis, and biological evaluation
K Meng, T Deng, M Liu, H Pu, Y Zhang, H Zou… - Bioorganic …, 2024 - Elsevier
A series of flavonol derivatives containing 1, 2, 4-triazole Schiff base was designed,
synthesized and tested for their biological activities. The results of the biological activity test …
synthesized and tested for their biological activities. The results of the biological activity test …
Synthesis, characterization, crystal structure, and molecular docking of o-vanillin and l-valine derived molecules: a DFT study and antiproliferative activity against the …
Cu (II) complexes 1 and 2 with and without a coligand (2, 2′-bipyridyl) were synthesized
using the ligand NaLH= 2-{(E)-[(2-hydroxy-3-methoxyphenyl) methylidene] amino}-3 …
using the ligand NaLH= 2-{(E)-[(2-hydroxy-3-methoxyphenyl) methylidene] amino}-3 …
Pyridine-Based Glycosides Bearing 1, 2, 4-Triazole and Their 1, 3, 4-oxadiazole analogues as Potential EGFR and CDK-2 Inhibitors: Design, Synthesis …
AF Kassem, A Younis, ES Nossier, HM Awad… - Journal of Molecular …, 2024 - Elsevier
The increasing toxicity of recently developed anticancer medications is seen as a serious
problem that stems from the variety of targets involved; as a result, more research on these …
problem that stems from the variety of targets involved; as a result, more research on these …
Tandem Synthesis and Computational Insights into Triazole and Pyrazole-Based Pyridine Derivatives Targeting EGFR-TK in Cancer Therapy
S Bondock, N Alabbad, RH Abd El-Aleam… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Cancer remains one of the leading causes of death worldwide, despite significant advances
in treatment. Targeting tyrosine kinases, such as the epidermal growth factor receptor …
in treatment. Targeting tyrosine kinases, such as the epidermal growth factor receptor …
Indole analogs as potential anti-breast cancer agents: Design, synthesis, in-vitro bioevaluation with DFT, molecular docking and ADMET studies
R Gavadia, J Rasgania, N Sahu, S Nimesh… - Journal of the Indian …, 2024 - Elsevier
Being a belligerent malignancy, triple-negative breast cancer poses unmet clinical
challenges due to lack of targeted therapy, rapid growth rate and metastasis, high …
challenges due to lack of targeted therapy, rapid growth rate and metastasis, high …
[HTML][HTML] Resveratrol-based Schiff base derivatives: Synthesis, characterization and cytotoxic study
LA Al-lehaib, EMM Ali, KO Al-Footy, HA Al-Ghamdi… - Results in …, 2024 - Elsevier
New resveratrol-based Schiff base derivatives (1, 2, 4-triazole Schiff base derivatives 5a-d
and hydrazide Schiff base derivatives 7a-d) were designed, synthesized via Schiff base …
and hydrazide Schiff base derivatives 7a-d) were designed, synthesized via Schiff base …
[PDF][PDF] Results in Chemistry
LA Al-lehaib, EMM Ali, KO Al-Footy, HA Al-Ghamdi - researchgate.net
New resveratrol-based Schiff base derivatives (1, 2, 4-triazole Schiff base derivatives 5a-d
and hydrazide Schiff base derivatives 7a-d) were designed, synthesized via Schiff base …
and hydrazide Schiff base derivatives 7a-d) were designed, synthesized via Schiff base …