Personalized cell therapy for patients with peripheral arterial diseases in the context of genetic alterations: artificial intelligence-based responder and non-responder …

AA Salybekov, M Wolfien, S Kobayashi, G Steinhoff… - Cells, 2021 - mdpi.com
Stem/progenitor cell transplantation is a potential novel therapeutic strategy to induce
angiogenesis in ischemic tissue, which can prevent major amputation in patients with …

Development of a polygenic risk score to improve detection of peripheral artery disease

F Wang, I Ghanzouri, NJ Leeper, PS Tsao… - Vascular …, 2022 - journals.sagepub.com
Introduction: Peripheral artery disease (PAD) is a major cause of cardiovascular morbidity
and mortality, yet timely diagnosis is elusive. Larger genome-wide association studies …

Hearing sensitivity, cardiovascular risk, and neurocognitive function: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

AM Stickel, W Tarraf, KE Bainbridge… - … –Head & Neck …, 2021 - jamanetwork.com
Importance Both cardiovascular disease risk and hearing impairment are associated with
cognitive dysfunction. However, the combined influence of the 2 risk factors on cognition is …

The high-dimensional space of human diseases built from diagnosis records and mapped to genetic loci

G Jia, Y Li, X Zhong, K Wang, M Pividori… - Nature Computational …, 2023 - nature.com
Human diseases are traditionally studied as singular, independent entities, limiting
researchers' capacity to view human illnesses as dependent states in a complex …

Peripheral artery disease in type 2 diabetes mellitus: survival analysis of an Ecuadorian population in primary care

F Barrera-Guarderas… - Journal of primary …, 2020 - journals.sagepub.com
Background Peripheral artery disease (PAD) is associated with cardiovascular risk in type 2
diabetes mellitus (DM). The ankle-brachial index (ABI) is used for diagnosis of PAD …

Genetics of Latin American Diversity (GLAD) Project: insights into population genetics and association studies in recently admixed groups in the Americas

V Borda, DP Loesch, B Guo, R Laboulaye… - bioRxiv, 2023 - biorxiv.org
Latin America is underrepresented in genetic studies, which can exacerbate disparities in
personalized genomic medicine. However, genetic data of thousands of Latin Americans are …

[HTML][HTML] Association between lifestyles, anthropometric measurements and peripheral arterial disease in public sector health workers

JV Chávez-Sosa, R Rojas-Humpire… - American journal of …, 2021 - ncbi.nlm.nih.gov
Introduction: Peripheral arterial disease (PAD) occurs when there is a narrowing of the blood
vessels outside the heart; this disease is concentrated in low and middle income countries …

Discerning asthma endotypes through comorbidity mapping

G Jia, X Zhong, HK Im, N Schoettler, M Pividori… - Nature …, 2022 - nature.com
Asthma is a heterogeneous, complex syndrome, and identifying asthma endotypes has
been challenging. We hypothesize that distinct endotypes of asthma arise in disparate …

Association between Circulating B‐Type Natriuretic Peptide and Diabetic Peripheral Neuropathy: A Cross‐Sectional Study of a Chinese Type 2 Diabetic Population

P Yan, Q Wan, Z Zhang, Y Xu, Y Miao… - Journal of Diabetes …, 2020 - Wiley Online Library
Cardiovascular disease which is associated with cardiac dysfunction, usually measured with
circulating levels of B‐type natriuretic peptide (BNP), has been associated with incidence …

[HTML][HTML] Epigenética y estilos de vida saludables de la Enfermedad Arterial Periférica

IJ Ángel-Solarte, G Acosta-Tapia, RE Álvarez-Rosero… - Entramado, 2022 - scielo.org.co
RESUMEN La Enfermedad Arterial Periférica (EAP) se caracteriza por la oclusión
progresiva de las arterias de las extremidades inferiores, afectando a gran parte de la …