Abstract Machine learning (ML) is increasingly recognized as a useful tool in healthcare
applications, including epilepsy. One of the most important applications of ML in epilepsy is …

Epilepsy is a common neurological disease in both humans and domestic dogs, making
dogs an ideal translational model of epilepsy. In both species, epilepsy is a complex brain …

Responsive neurostimulation (RNS) devices, able to detect imminent seizures and to rapidly
deliver electrical stimulation to the brain, are effective in reducing seizures in some patients …

The location of interictal spikes is used to aid surgical planning in patients with medically
refractory epilepsy; however, their spatial and temporal dynamics are poorly understood. In …

Abstract Purpose of Review: The endogenous circadian rhythms are one of the cardinal
processes that control sleep. They are self-sustaining biological rhythms with a periodicity of …

Intracranial electrophysiological recording in patients with refractory focal epilepsy is the
gold standard for defining epileptogenic tissue. Although the concordance of intracranial …

Transient bioelectronics has grown fast, opening possibilities never thought before. In
medicine, transient implantable devices are interesting because they could eliminate the …

Objective. Implanting subdural and penetrating electrodes in the brain causes acute trauma
and inflammation that affect intracranial electroencephalographic (iEEG) recordings. This …

Personalized medicine requires that treatments adapt to not only the patient but also
changing factors within each individual. Although epilepsy is a dynamic disorder …

Objective The medial temporal lobe (MTL) encodes and recalls memories and can be a
predominant site for interictal spikes (IS) in patients with focal epilepsy. It is unclear whether …