Estrogen receptors in pain modulation: cellular signaling

Q Chen, W Zhang, N Sadana, X Chen - Biology of sex Differences, 2021 - Springer
Sensory perception and emotional disorders are disproportionally represented in men and
women and are thus thought to be modulated by different sex hormones in various …

Molecular determinants of cardiac transient outward potassium current (Ito) expression and regulation

N Niwa, JM Nerbonne - Journal of molecular and cellular cardiology, 2010 - Elsevier
Rapidly activating and inactivating cardiac transient outward K+ currents, Ito, are expressed
in most mammalian cardiomyocytes, and contribute importantly to the early phase of action …

[HTML][HTML] PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior

J Zhao, S Bang, K Furutani, A McGinnis, C Jiang… - Neuron, 2023 - cell.com
Summary Programmed death protein 1 (PD-1) and its ligand PD-L1 constitute an immune
checkpoint pathway. We report that neuronal PD-1 signaling regulates learning/memory in …

The kv4. 2 potassium channel subunit is required for pain plasticity

HJ Hu, Y Carrasquillo, F Karim, WE Jung… - Neuron, 2006 - cell.com
A-type potassium currents are important determinants of neuronal excitability. In spinal cord
dorsal horn neurons, A-type currents are modulated by extracellular signal-regulated …

Activation of EGFR and ERK by rhomboid signaling regulates the consolidation and maintenance of sleep in Drosophila

K Foltenyi, RJ Greenspan, JW Newport - Nature neuroscience, 2007 - nature.com
Epidermal growth factor receptor (EGFR) signaling in the mammalian hypothalamus is
important in the circadian regulation of activity. We have examined the role of this pathway in …

Rapid changes in hippocampal CA1 pyramidal cell function via pre‐as well as postsynaptic membrane mineralocorticoid receptors

JE Olijslagers, ER De Kloet, Y Elgersma… - European Journal of …, 2008 - Wiley Online Library
Corticosterone (100 nm) rapidly increases the frequency of miniature excitatory postsynaptic
currents in mouse CA1 pyramidal neurons via membrane‐located mineralocorticoid …

Dendritic ion channel trafficking and plasticity

MM Shah, RS Hammond, DA Hoffman - Trends in neurosciences, 2010 - cell.com
Dendritic ion channels are essential for the regulation of intrinsic excitability as well as
modulating the shape and integration of synaptic signals. Changes in dendritic channel …

Mouse Cntnap2 and Human CNTNAP2 ASD Alleles Cell Autonomously Regulate PV+ Cortical Interneurons

D Vogt, KKA Cho, SM Shelton, A Paul, ZJ Huang… - Cerebral …, 2018 - academic.oup.com
Human mutations in CNTNAP2 are associated with an array of neuropsychiatric and
neurological syndromes, including speech and language disorders, epilepsy, and autism …

Mechanisms of pain modulation by sex hormones in migraine

S Gupta, KE McCarson, KMA Welch… - … : The Journal of Head …, 2011 - Wiley Online Library
(Headache 2011; 51: 905‐922) A number of pain conditions, acute as well as chronic, are
much more prevalent in women, such as temporomandibular disorder (TMD), irritable bowel …

Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2. 1

PT Redman, K He, KA Hartnett… - Proceedings of the …, 2007 - National Acad Sciences
Kv2. 1, the primary delayed rectifying potassium channel in neurons, is extensively
regulated by phosphorylation. Previous reports have described Kv2. 1 phosphorylation …