Arginine metabolism and nutrition in growth, health and disease

G Wu, FW Bazer, TA Davis, SW Kim, P Li… - Amino acids, 2009 - Springer
Abstract l-Arginine (Arg) is synthesised from glutamine, glutamate, and proline via the
intestinal-renal axis in humans and most other mammals (including pigs, sheep and rats) …

Pathogenesis of preeclampsia

BC Young, RJ Levine… - Annual Review of …, 2010 - annualreviews.org
Preeclampsia is a systemic syndrome that occurs in 3 to 5% of pregnant women and
classically manifests as new-onset hypertension and proteinuria after 20 weeks of gestation …

Pathophysiology of the clinical manifestations of preeclampsia

M Hladunewich, SA Karumanchi… - Clinical Journal of the …, 2007 - journals.lww.com
Five to 7% of all pregnancies are complicated by pre-eclampsia. Proteinuria and
hypertension dominate the clinical picture, because the chief target organ is the kidney …

Arginine: clinical potential of a semi-essential amino acid.(Arginine)

J Appleton - Alternative medicine review, 2002 - go.gale.com
Arginine, a semi-essential amino acid, is involved in numerous areas of human
biochemistry, including ammonia detoxification, hormone secretion, and immune …

Arginine nutrition in development, health and disease

G Wu, CJ Meininger, DA Knabe, FW Baze… - Current Opinion in …, 2000 - journals.lww.com
As a precursor of nitric oxide, polyamines and other molecules with enormous biologic
importance, L-arginine plays versatile key roles in nutrition and metabolism. Arginine is an …

Nitric oxide and its role during pregnancy: from ovulation to delivery

H Maul, M Longo, GR Saade… - Current pharmaceutical …, 2003 - ingentaconnect.com
Nitric oxide (NO) is a major paracrine mediator and important regulatory agent in various
female reproductive processes, such as ovulation, implantation, pregnancy maintenance …

Nitric oxide dysfunction in the pathophysiology of preeclampsia

DT Lowe - Nitric oxide, 2000 - Elsevier
Researchers disagree as to the importance of nitric oxide (NO) in preeclampsia. Many
researchers have alluded to NO's possible primary or secondary role in the development of …

Increased circulating concentrations of asymmetric dimethyl arginine (ADMA), an endogenous inhibitor of nitric oxide synthesis, in preeclampsia

A Pettersson, T Hedner, I Milsom - Acta obstetricia et gynecologica …, 1998 - Taylor & Francis
Objectives. To study endogenous nitric oxide (NO) synthesis inhibitors in preeclampsia by
measuring asymmetric dimethyl arginine (ADMA) and arginine. Study design. Blood …

Effects of prolonged oral supplementation with l‐arginine on blood pressure and nitric oxide synthesis in preeclampsia

K Rytlewski, R Olszanecki, R Korbut… - European journal of …, 2005 - Wiley Online Library
Background Several lines of evidence point to the dysfunction of the endothelial l‐arginine–
NO system in preeclampsia. We investigated the influence of dietary supplementation with l …

Impact of arginine nutrition and metabolism during pregnancy on offspring outcomes

CN Hsu, YL Tain - Nutrients, 2019 - mdpi.com
By serving as a precursor for the synthesis of nitric oxide, polyamines, and other molecules
with biological importance, arginine plays a key role in pregnancy and fetal development …