Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment
RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …
functioning associated with the disorder and are not responsive to existing treatments. In this …
Disorder, not just state of risk: meta-analysis of functioning and quality of life in people at high risk of psychosis
BackgroundThe nosology of the psychosis high-risk state is controversial. Traditionally
conceived as an 'at risk'state for the development of psychotic disorders, it is also …
conceived as an 'at risk'state for the development of psychotic disorders, it is also …
Individual differences in the executive control of attention, memory, and thought, and their associations with schizotypy.
Abstract [Correction Notice: An Erratum for this article was reported in Vol 145 (12) of
Journal of Experimental Psychology: General (see record 2016-57218-003). There were …
Journal of Experimental Psychology: General (see record 2016-57218-003). There were …
Abnormalities in hubs location and nodes centrality predict cognitive slowing and increased performance variability in first-episode schizophrenia patients
Abstract Introducing the Minimum Spanning Tree (MST) algorithms to neural networks
science eliminated the problem of arbitrary setting of the threshold for connectivity strength …
science eliminated the problem of arbitrary setting of the threshold for connectivity strength …
Cognitive variability predicts incident Alzheimer's disease and mild cognitive impairment comparable to a cerebrospinal fluid biomarker
CE Gleason, D Norton, ED Anderson… - Journal of …, 2017 - journals.sagepub.com
Background: Alzheimer's disease (AD) biomarkers are emerging as critically important for
disease detection and monitoring. Most biomarkers are obtained through invasive, resource …
disease detection and monitoring. Most biomarkers are obtained through invasive, resource …
16p11 duplication disrupts hippocampal-orbitofrontal-amygdala connectivity, revealing a neural circuit endophenotype for schizophrenia
GC Bristow, DM Thomson, RL Openshaw, EJ Mitchell… - Cell reports, 2020 - cell.com
Summary Chromosome 16p11. 2 duplications dramatically increase risk for schizophrenia,
but the mechanisms remain largely unknown. Here, we show that mice with an equivalent …
but the mechanisms remain largely unknown. Here, we show that mice with an equivalent …
Executive control fluctuations underlie behavioral variability in anthropoids
In complex tasks requiring cognitive control, humans show trial-by-trial alterations in
response time (RT), which are evident even when sensory-motor or other contextual aspects …
response time (RT), which are evident even when sensory-motor or other contextual aspects …
Cognitive control and schizophrenia: The greatest reliability of the Stroop task
C Laurenson, P Gorwood, M Orsat, JP Lhuillier… - Psychiatry …, 2015 - Elsevier
Three components of cognitive inhibition were compared in patients with schizophrenia and
healthy controls. Nineteen patients with schizophrenia were compared to 30 healthy …
healthy controls. Nineteen patients with schizophrenia were compared to 30 healthy …
Within-individual variability in cognitive performance in schizophrenia: a narrative review of the key literature and proposed research agenda
Schizophrenia is a neurodevelopmental disorder and a leading cause of disability
worldwide. Deficits in cognitive function are characteristic of schizophrenia and are …
worldwide. Deficits in cognitive function are characteristic of schizophrenia and are …
Cognitive variability—A marker for incident MCI and AD: An analysis for the Alzheimer's Disease Neuroimaging Initiative
ED Anderson, M Wahoske, M Huber, D Norton… - Alzheimer's & Dementia …, 2016 - Elsevier
Introduction The potential of intra-individual cognitive variability (IICV) to predict incident
mild cognitive impairment (MCI) or Alzheimer's disease (AD) was examined and compared …
mild cognitive impairment (MCI) or Alzheimer's disease (AD) was examined and compared …