Bacterial multidrug efflux pumps have come to prominence in human and veterinary
pathogenesis because they help bacteria protect themselves against the antimicrobials …

The polymyxin and lipopeptide classes of antibiotics are membrane-targeting drugs of last
resort used to treat infections caused by multi-drug-resistant pathogens. Despite similar …

Staphylococcus aureus frequently causes infections that are challenging to treat, leading to
high rates of persistent and relapsing infection. Here, to understand how the host …

The microorganisms that have developed resistance to available therapeutic agents are
threatening the globe and multidrug resistance among the bacterial pathogens is becoming …

Antibiotic resistance is a serious public health concern, and new drugs are needed to
ensure effective treatment of many bacterial infections. Bacterial type II fatty acid synthesis …

The symbiotic association between bacterial symbionts and insect hosts is a complicated
process that is not completely understood. Herein, we used a silkworm model to study the …

The rapid emergence and spread of antibiotic-resistant bacteria continues to be an issue
difficult to deal with, especially in the clinical, animal husbandry, and food fields. The …

Antimicrobial resistance is a major global health challenge. As few new efficacious
antibiotics will become available in the near future, peptide antibiotics continue to be major …

Daptomycin (DAP), a cyclic lipopeptide produced by Streptomyces roseosporus, is a novel
antibiotic to clinically treat various Gram‐positive pathogenic bacteria‐induced infections …

Background: Carvacrol, a mono-terpenoid phenol found in herbs, such as oregano and
thyme, has excellent antibacterial properties against Streptococcus pyogenes. However, its …