Parkinson's disease (PD) is characterized by a range of motor symptoms. Besides the
cardinal symptoms (akinesia and bradykinesia, tremor and rigidity), PD patients show …

Dementia and gait impairments often coexist in older adults and patients with
neurodegenerative disease. Both conditions represent independent risk factors for falls. The …

The right middle fontal gyrus (MFG) has been proposed to be a site of convergence of the
dorsal and ventral attention networks, by serving as a circuit-breaker to interrupt ongoing …

The differential diagnosis of parkinsonian syndromes is considered one of the most
challenging in neurology and error rates in the clinical diagnosis can be high even at …

Objective Postural instability and gait difficulties (PIGDs) represent debilitating disturbances
in Parkinson's disease (PD). Past acetylcholinesterase positron emission tomography (PET) …

Recent years have shown the critical importance of inter-regional neural network
connectivity in supporting healthy brain function. Such connectivity is measurable using …

Diverse but complementary methodologies are required to uncover the complex
determinants and pathophysiology of freezing of gait. To develop future therapeutic …

Oscillatory activities across multiple frequency bands and their cross-frequency interactions
within spatially segregated loops of the basal ganglia-thalamo-cortical system may relate to …

Freezing of gait (FOG) is a very disabling and common gait disorder in Parkinson's disease
(PD). The first aim of this article was to provide a methodological and critical review of the …

Recent neuroimaging evidence has led to the proposal that freezing of gait in Parkinson's
disease is due to dysfunctional interactions between frontoparietal cortical regions and …