Methotrexate and interstitial lung disease: controversies and questions. A narrative review of the literature

GE Fragoulis, R Conway, E Nikiphorou - Rheumatology, 2019 - academic.oup.com
MTX, which is the anchor-drug for the treatment of RA, has been associated with lung injury
and in particular with MTX-related pneumonitis (M-pneu). Although the frequency of M-pneu …

Role of autoantibodies in the diagnosis and prognosis of interstitial lung disease in autoimmune rheumatic disorders

M Kuwana, A Gil-Vila… - Therapeutic Advances …, 2021 - journals.sagepub.com
Interstitial lung disease (ILD) has been recognized as a frequent manifestation associated
with a substantial morbidity and mortality burden in patients with autoimmune rheumatic …

Rheumatoid arthritis disease activity predicting incident clinically apparent rheumatoid arthritis–associated interstitial lung disease: a prospective cohort study

JA Sparks, X He, J Huang, EA Fletcher… - Arthritis & …, 2019 - Wiley Online Library
Objective To evaluate rheumatoid arthritis (RA) disease activity and risk of RA‐associated
interstitial lung disease (RA‐ILD). Methods We investigated disease activity and risk of RA …

Citrullinated vimentin mediates development and progression of lung fibrosis

FJ Li, R Surolia, H Li, Z Wang, G Liu… - Science translational …, 2021 - science.org
The mechanisms by which environmental exposures contribute to the pathogenesis of lung
fibrosis are unclear. Here, we demonstrate an increase in cadmium (Cd) and carbon black …

Lifestyle and clinical risk factors for incident rheumatoid arthritis-associated interstitial lung disease

VL Kronzer, W Huang, PF Dellaripa, S Huang… - The Journal of …, 2021 - jrheum.org
Objective To determine the association between novel lifestyle factors on risk of rheumatoid
arthritis (RA)-associated interstitial lung disease (ILD), define the threshold at which smoking …

[PDF][PDF] One year in review 2016: pathogenesis of rheumatoid arthritis

E Bellucci, R Terenzi, GM La Paglia… - Clin Exp …, 2016 - academia.edu
Rheumatoid arthritis (RA) is an autoimmune disease characterised by chronic synovial
inlammation leading to joint destruction and bone erosions. Although the pathogenic …

Two sides of the same coin? A review of the similarities and differences between idiopathic pulmonary fibrosis and rheumatoid arthritis-associated interstitial lung …

S Matson, J Lee, O Eickelberg - European Respiratory Journal, 2021 - Eur Respiratory Soc
Rheumatoid arthritis associated interstitial lung disease (RA-ILD) and idiopathic pulmonary
fibrosis (IPF) are distinct diseases; however, they share several clinical, radiographic and …

[PDF][PDF] Rheumatoid arthritis-associated interstitial lung disease: epidemiology, risk/prognostic factors, and treatment landscape

MS Fazeli, V Khaychuk, K Wittstock, X Han… - Clin Exp …, 2021 - clinexprheumatol.org
Objective. To summarise the epidemiology, risk and prognostic factors, and treatment
landscape of rheumatoid arthritis-associated interstitial lung disease (RA-ILD). Methods …

Rituximab therapy in interstitial lung disease associated with rheumatoid arthritis

A Fui, L Bergantini, E Selvi, MA Mazzei… - Internal medicine …, 2020 - Wiley Online Library
Background: Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease. In this
disease, interstitial lung diseases (ILD) is associated with high risk of mortality. Rituximab, a …

Lung involvements in rheumatic diseases: update on the epidemiology, pathogenesis, clinical features, and treatment

YJ Ha, YJ Lee, EH Kang - BioMed research international, 2018 - Wiley Online Library
Lung illness encountered in patients with rheumatic diseases bears clinical significance in
terms of increased morbidity and mortality as well as potential challenges placed on patient …