Technological innovations in photochemistry for organic synthesis: flow chemistry, high-throughput experimentation, scale-up, and photoelectrochemistry

L Buglioni, F Raymenants, A Slattery… - Chemical …, 2021 - ACS Publications
Photoinduced chemical transformations have received in recent years a tremendous amount
of attention, providing a plethora of opportunities to synthetic organic chemists. However …

[HTML][HTML] Recent advances in visible light-activated radical coupling reactions triggered by (i) ruthenium,(ii) iridium and (iii) organic photoredox agents

JD Bell, JA Murphy - Chemical Society Reviews, 2021 - pubs.rsc.org
Photoredox chemistry with organic or transition metal agents has been reviewed in earlier
years, but such is the pace of progress that we will overlap very little with earlier …

Energy transfer catalysis mediated by visible light: principles, applications, directions

F Strieth-Kalthoff, MJ James, M Teders… - Chemical Society …, 2018 - pubs.rsc.org
Harnessing visible light to access excited (triplet) states of organic compounds can enable
impressive reactivity modes. This tutorial review covers the photophysical fundamentals and …

Mechanistic studies in photocatalysis

L Buzzetti, GEM Crisenza… - Angewandte Chemie …, 2019 - Wiley Online Library
The fast‐moving fields of photoredox and photocatalysis have recently provided fresh
opportunities to expand the potential of synthetic organic chemistry. Advances in light …

Deaminative Strategy for the Visible‐Light‐Mediated Generation of Alkyl Radicals

FJR Klauck, MJ James, F Glorius - … Chemie International Edition, 2017 - Wiley Online Library
A deaminative strategy for the visible‐light‐mediated generation of alkyl radicals from redox‐
activated primary amine precursors is described. Abundant and inexpensive primary amine …

How to explore chemical space using algorithms and automation

PS Gromski, AB Henson, JM Granda… - Nature Reviews …, 2019 - nature.com
Although extending the reactivity of a given class of molecules is relatively straightforward,
the discovery of genuinely new reactivity and the molecules that result is a wholly more …

Visible-Light-Promoted Activation of Unactivated C(sp3)–H Bonds and Their Selective Trifluoromethylthiolation

S Mukherjee, B Maji, A Tlahuext-Aca… - Journal of the American …, 2016 - ACS Publications
Selective functionalization of ubiquitous C (sp3)–H bonds using visible light is a highly
challenging yet desirable goal in organic synthesis. The development of such processes …

Design and optimization of catalysts based on mechanistic insights derived from quantum chemical reaction modeling

S Ahn, M Hong, M Sundararajan, DH Ess… - Chemical …, 2019 - ACS Publications
Until recently, computational tools were mainly used to explain chemical reactions after
experimental results were obtained. With the rapid development of software and hardware …

The energy-transfer-enabled biocompatible disulfide–ene reaction

M Teders, C Henkel, L Anhäuser, F Strieth-Kalthoff… - Nature Chemistry, 2018 - nature.com
Sulfur-containing molecules participate in many essential biological processes. Of utmost
importance is the methylthioether moiety, present in the proteinogenic amino acid …

High throughput strategies for the discovery and optimization of catalytic reactions

ES Isbrandt, RJ Sullivan… - Angewandte Chemie …, 2019 - Wiley Online Library
Homogeneous catalysis has provided chemists with numerous transformations to enable
rapid construction of organic molecules. However, these reactions are complex, requiring …