Expert consensus and evidence-based recommendations for the assessment of flow-mediated dilation in humans

DHJ Thijssen, RM Bruno, ACCM van Mil… - European heart …, 2019 - academic.oup.com
Endothelial dysfunction is involved in the development of atherosclerosis, which precedes
asymptomatic structural vascular alterations as well as clinical manifestations of …

[HTML][HTML] Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies

R Kaur, M Kaur, J Singh - Cardiovascular diabetology, 2018 - Springer
The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …

[HTML][HTML] Role of free fatty acids in endothelial dysfunction

A Ghosh, L Gao, A Thakur, PM Siu, CWK Lai - Journal of biomedical …, 2017 - Springer
Plasma free fatty acids levels are increased in subjects with obesity and type 2 diabetes,
playing detrimental roles in the pathogenesis of atherosclerosis and cardiovascular …

Endothelial function in cardiovascular medicine: a consensus paper of the European society of cardiology working groups on atherosclerosis and vascular biology …

Y Alexander, E Osto, A Schmidt-Trucksäss… - Cardiovascular …, 2021 - academic.oup.com
Endothelial cells (ECs) are sentinels of cardiovascular health. Their function is reduced by
the presence of cardiovascular risk factors, and is regained once pathological stimuli are …

Molecular mechanism involved in cyclophosphamide-induced cardiotoxicity: Old drug with a new vision

A Iqubal, MK Iqubal, S Sharma, MA Ansari, AK Najmi… - Life sciences, 2019 - Elsevier
Cyclophosphamide (CP) is an important anticancer drug which belongs to the class of
alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation …

[HTML][HTML] Effects of l-Arginine Plus Vitamin C Supplementation on Physical Performance, Endothelial Function, and Persistent Fatigue in Adults with Long COVID: A …

M Tosato, R Calvani, A Picca, F Ciciarello, V Galluzzo… - Nutrients, 2022 - mdpi.com
Long COVID, a condition characterized by symptom and/or sign persistence following an
acute COVID-19 episode, is associated with reduced physical performance and endothelial …

Coronary heart disease risk: low-density lipoprotein and beyond

GE Shaya, TM Leucker, SR Jones, SS Martin… - Trends in cardiovascular …, 2022 - Elsevier
Coronary heart disease (CHD) is the leading cause of morbidity and mortality world-wide
and has been characterized as a chronic immunoinflammatory, fibroproliferative disease …

The assessment of endothelial function: from research into clinical practice

AJ Flammer, T Anderson, DS Celermajer, MA Creager… - Circulation, 2012 - Am Heart Assoc
The discovery of nitric oxide (NO) as a crucial endothe-lium-derived molecule for vascular
relaxation and the recognition of the endothelium as more than a passive interface between …

[HTML][HTML] Regulation of coronary blood flow

AG Goodwill, GM Dick, AM Kiel… - Comprehensive …, 2017 - ncbi.nlm.nih.gov
The heart is uniquely responsible for providing its own blood supply through the coronary
circulation. Regulation of coronary blood flow is quite complex and, after over 100 years of …

[HTML][HTML] Pathological effects of ionizing radiation: endothelial activation and dysfunction

B Baselet, P Sonveaux, S Baatout, A Aerts - Cellular and molecular life …, 2019 - Springer
The endothelium, a tissue that forms a single layer of cells lining various organs and cavities
of the body, especially the heart and blood as well as lymphatic vessels, plays a complex …