Among the various disorders that manifest with gait disturbance, cognitive impairment, and
urinary incontinence in the elderly population, idiopathic normal pressure hydrocephalus …

The devastating effects of the still incurable Alzheimer's disease (AD) project an ever
increasing shadow of burden on the health care system and society in general. In this …

In the past 8 years, both the International Working Group (IWG) and the US National Institute
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …

Amyloid imaging is currently introduced to the market for clinical use. We will review the
evidence demonstrating that the different amyloid PET ligands that are currently available …

Importance In vivo imaging of brain β-amyloid, a hallmark of Alzheimer disease, may assist
in the clinical assessment of suspected Alzheimer disease. Objective To determine the …

In vivo imaging of fibrillar β-amyloid deposits may assist clinical diagnosis of Alzheimer's
disease (AD), aid treatment selection for patients, assist clinical trials of therapeutic drugs …

Imaging fibrillar amyloid-β deposition in the human brain in vivo by positron emission
tomography has improved our understanding of the time course of amyloid-β pathology in …

Introduction Performance of the amyloid tracer [18 F] flutemetamol was evaluated against
three pathology standard of truth (SoT) measures including neuritic plaques (CERAD …

Objectives An electronic training programme (ETP) was developed for interpretation of
images during routine clinical use of the PET amyloid imaging agent [18 F] flutemetamol …

In Alzheimer's disease (AD), the deposition of β-amyloid (Aβ) is hypothesized to result in a
series of secondary neurodegenerative processes, leading ultimately to synaptic dysfunction …