Effects of naringin on oxidative stress, inflammation, some reproductive parameters, and apoptosis in acrylamide‐induced testis toxicity in rat

E Sengul, V Gelen, S Yildirim, İ Cinar… - Environmental …, 2023 - Wiley Online Library
Acrylamide (ACR) is used in many fields such as cosmetics, paper, and textile industries. It
also occurs at very high temperatures in some foods. Gonadotoxic effects of ACR have been …

Anticancer drugs paclitaxel, carboplatin, doxorubicin, and cyclophosphamide alter the biophysical characteristics of red blood cells, in vitro

E Skverchinskaya, N Levdarovich, A Ivanov… - Biology, 2023 - mdpi.com
Simple Summary An important issue in cancer chemotherapy is minimizing its side effects.
The extreme toxicity of chemotherapy drugs is due to their task of preventing the …

Antioxidative and analgesic effects of naringin through selective inhibition of transient receptor potential vanilloid member 1

S Eom, BB Lee, S Lee, Y Park, HD Yeom, TH Kim… - Antioxidants, 2021 - mdpi.com
Transient receptor potential vanilloid member 1 (TRPV1) is activated in response to
capsaicin, protons, temperature, and free reactive oxygen species (ROS) released from …

Naringin prevents diabetic nephropathy in rats through blockage of oxidative stress and attenuation of the mitochondrial dysfunction

A Pérez, J Mukdsi, L Valdez… - Canadian Journal of …, 2023 - cdnsciencepub.com
We have studied the effects of naringin (NAR), a flavonoid from citric fruits, on morphology,
ultrastructure and function of the kidney in streptozotocin (STZ)-induced diabetic rats. Two …

[HTML][HTML] Identification of the key mechanisms of action of Si-Ni-San in uveitis using bioinformatics and network pharmacology

D Zhang, L Hong, RS Zhang, Q Zhang, J Yao, J Wang… - Medicine, 2023 - journals.lww.com
Background: Uveitis is an eye disease with a high rate of blindness, whose pathogenesis is
not completely understood. Si-Ni-San (SNS) has been used as a traditional medicine to treat …

The Ameliorative Effect of Betulinic Acid on Oxidative Stress in Mice of Cyclophosphamide‐Induced Liver Damage

Y Huang, C Ma, L Zhu, L Kong, C Huang… - Environmental …, 2024 - Wiley Online Library
As a conventional immunosuppressive drug, cyclophosphamide (CYP) exhibits strong
hepatotoxicity in clinical applications. Betulinic acid (BA) is a natural triterpenoid that …

[HTML][HTML] Hesperetin-7-rutinoside mitigates erythrocyte dyslipidemia and oxidative stress induced by dichlorvos

AJ Akamo, AO Ojelabi, NM Akamo, BA Olagunju… - Journal of Hazardous …, 2024 - Elsevier
In many rural and semi-urban areas of Nigeria, dichlorvos (DDVP) is a commonly utilized
pesticide. However, it provokes remarkable health hazards, including erythrocyte toxicity …

[HTML][HTML] Molecular Docking, Bioinformatic Analysis, and Experimental Verification for the Effect of Naringin on ADHD: Possible Inhibition of GSK-3β and HSP90

HI Mokhtar, SA Zaitone, K El-Sayed, RM Lashine… - Pharmaceuticals, 2024 - mdpi.com
Background/Objectives: One of the most abundant and growing neurodevelopmental
disorders in recent decades is attention deficit hyperactivity disorder (ADHD). Many trials …

[HTML][HTML] Morin mitigate diethyl phthalate and bisphenol s–Induced hematotoxicity in rats model by abrogating oxidative stress

OE Eteng, CA Moses, CU Ogbonna, AO Adeleye… - Pharmacological …, 2022 - Elsevier
Endocrine disruptors affect biological systems, some as neglected home producing toxicity
(NHPT). We investigated the effect of morin on diethyl phthalate (DEP) and bisphenol S …

Investigating In silico and In vitro Therapeutic Potential of Diosmetin as the Anti-Parkinson Agent

KK Varshney, JK Gupta, R Srivastava - Protein & Peptide Letters, 2024 - benthamdirect.com
Aim This study aimed to investigate how diosmetin interacts with seven target receptors
associated with oxidative stress (OS) and validate its antioxidant properties for the potential …