Pharmacological alterations in dopamine transporter (DAT) function not only modulate
dopamine reuptake, but they can induce rapid changes in the plasmalemmal expression of …

Na+/Cl–-dependent neurotransmitter transporters, which constitute a gene superfamily, are
crucial for limiting neurotransmitter activity. Thus, it is critical to understand their regulation …

The dopamine transporter (DAT) regulates the clearance of dopamine (DA) released into the
extracellular space and is an important site on which psychostimulants act to produce their …

Gene expression analysis implicates an increasing number of novel genes in the brain as
potential targets for the treatment of neurological and psychiatric disorders. Frequently …

Antidepressant-sensitive serotonin (5-hydroxytrypta-mine, 5HT) transporters (SERTs) are
responsible for efficient synaptic clearance of extracellular 5HT. Previously (Qian, Y., Galli …

Presynaptic transporter proteins regulate the clearance of extracellular biogenic amines
after release and are important targets for multiple psychoactive agents, including …

Receptor-mediated feedback control plays an important role in dopamine (DA)
neurotransmission. Recent evidence suggests that release and uptake, key mechanisms …

We have hypothesized that the midbrain dopamine (DA) neurons are a target for insulin
action in the central nervous system (CNS). In support of this hypothesis, we have previously …

The dopamine (DA) transporter (DAT) controls dopaminergic neurotransmission by
removing extracellular DA. Although DA reuptake is proposed to be regulated by DAT traffic …

It is well accepted that methylphenidate (MPD) inhibits dopamine (DA) transporter function.
In addition to this effect, this study demonstrates that MPD increases vesicular [3H] DA …