Fluorine-containing small molecules have occupied an especial position in drug discovery
research. The successful clinical use of fluorinated corticosteroids in the 1950s and …

Simple Summary Ovarian cancer is a lethal disease in women with a 10-year survival rate
of< 40% worldwide. A key molecular alteration in ovarian cancer is the aberrant …

Epithelial ovarian cancer (EOC) remains one of the leading causes of cancer-related deaths
among women worldwide. Receptor tyrosine kinases (RTKs) have long been sought as …

Ovarian cancer, one of the deadliest malignancies in female cancer patients, is
characterized by recurrence and poor response to cytotoxic chemotherapies. Fewer than …

Introduction: Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy
worldwide and despite an initial response to therapeutic agents, the majority of patients …

Poor chemotherapy response remains a major treatment challenge for high‐grade serous
ovarian cancer (HGSC). Cancer stem cells are the major contributors to relapse and …

Ovarian cancer is the most lethal gynecologic malignancy. About 75% of ovarian cancer
patients relapse and/or develop chemo‐resistant disease after initial response to standard …

Aurora kinases (AURK) are key regulators of the mitotic spindle formation. AURK is
frequently overexpressed in ovarian cancer and this overexpression has been frequently …

Epithelial ovarian cancer (EOC) has exhibited marginal improvement in survival rate,
despite advances in surgical debulking and chemotherapy regimens. Although the majority …

Ovarian cancer is the second most lethal gynecological cancer worldwide and while most
patients respond to initial therapy, they often relapse with resistant disease. Human …