Macronutrients–carbohydrates, fats, and proteins–supply the nutrients required for optimal
functioning. Inadequate intake compromises both physical and brain health. We synthesized …

Macroautophagy (hereafter autophagy) is an evolutionarily highly conserved cellular
process that participates in the maintenance of intracellular homeostasis through the …

Emerging evidence that autophagy serves as a sweeper for toxic materials in the brain gives
us new insight into the pathophysiology of neurodegenerative diseases. Autophagy is …

Background Current evidence suggests a central role for autophagy in many
neurodegenerative diseases including Alzheimer's disease, Huntington's disease …

Experimental and clinical data support the neuroprotective properties of the ketogenic diet
and ketone bodies, but there is still a lot to discover to comprehensively understand the …

There are no studies examining the effects of 3, 3′-diindolylmethane (DIM) in neuronal
cells subjected to ischemia. Little is also known about the roles of apoptosis and autophagy …

Brain ischemia is a major cause of adult disability and death, and it represents a worldwide
health problem with significant economic burden for modern society. The identification of the …

Hydrogen sulfide (H2S), the third gas transmitter, has been proven to be neuroprotective in
cerebral ischemic injury, but whether its effect is mediated by regulating autophagy is not yet …

We once reported that P‐glycoprotein (P‐GP) and multidrug resistance‐associated protein 2
(MRP 2) were oppositely regulated at the blood–brain barrier (BBB) of thioacetamide …

Abstract Hydrogen sulfide (H 2 S), an endogenous gaseous signal molecule, exhibits
protective effect against ischemic injury. However, its underlying mechanism is not fully …