First-degree relatives of individuals with late-onset Alzheimer's disease (LOAD) are at
increased risk for developing dementia, yet the associations between family history of LOAD …

Objectives: There is currently a lack of consensus among neuropsychologists about which
cognitive assessment paradigms hold the most promise in identifying subtle cognitive …

Objective Semantic intrusion (SI) errors may highlight specific breakdowns in memory
associated with preclinical Alzheimer disease (AD); however, there have been no …

Objective: Prior to evidence of episodic memory decline, a lengthy preclinical phase of
Alzheimer's disease (AD) exists characterized by the build-up of tau pathology within …

Introduction Culturally fair cognitive assessments sensitive to detecting changes associated
with prodromal Alzheimer's disease are needed. Methods Performance of Hispanic and non …

Introduction: Among persons with amnestic mild cognitive impairment (aMCI), intrusion
errors on subscales that measure proactive semantic interference (PSI) may be among the …

Despite the growing emphasis to identify early biological markers that can detect the
progressive accumulation of brain pathology in the complex pathophysiologic cascade that …

Introduction This study investigated the role of proactive semantic interference (frPSI) in
predicting the progression of amnestic Mild Cognitive Impairment (aMCI) to dementia, taking …

Background The development and validation of clinical outcome measures to detect early
cognitive decline associated with Alzheimer's disease (AD) biomarkers is imperative …

Cognitive-behavioral testing in preclinical models of Alzheimer's disease has failed to
capture deficits in goal-directed action control. Here, we provide the first comprehensive …