Chimeric antigen receptor (CAR)-T cell therapy represents a landmark advance in
personalized cancer treatment. CAR-T strategy generally engineers T cells from a specific …

With the development of bone tissue engineering bio-scaffold materials by adding metallic
ions to improve bone healing have been extensively explored in the past decades …

Regulating macrophage activation precisely is crucial in treating chronic inflammation in
osteoarthritis (OA). However, the stable pro-inflammatory state and deep distribution of …

Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …

We previously reported that IGFBP7 plays a role in maintaining mRNA stability of oncogenic
lncRNA UBE2CP3 by RNA-RNA interaction in gastric cancer (GC). Clinical cohort studies …

High-grade glioma is one of the deadliest primary tumors of the central nervous system.
Despite the many novel immunotherapies currently in development, it has been difficult to …

Summary T helper type 2 (Th2) cytokine-activated M2 macrophages contribute to
inflammation resolution and wound healing. This study shows that IL-4-primed …

Strategies that can selectively eliminate senescent cells (SnCs), namely senolytics, have
been shown to promote healthy lifespan. However, it is challenging to achieve precise …

Tumor‐associated macrophages (TAMs) are the most prominent immune cells in the breast
cancer microenvironment, and the protumor functions of TAMs are thought to affect cancer …

Fracture healing is a complex biological process that involves the orchestrated interplay of
various cells and molecular signaling pathways. Among the key players, macrophages have …