The pathogenesis of Ebola virus disease
L Baseler, DS Chertow, KM Johnson… - Annual Review of …, 2017 - annualreviews.org
For almost 50 years, ebolaviruses and related filoviruses have been repeatedly reemerging
across the vast equatorial belt of the African continent to cause epidemics of highly fatal …
across the vast equatorial belt of the African continent to cause epidemics of highly fatal …
[PDF][PDF] Protein stability: a crystallographer's perspective
Protein stability is a topic of major interest for the biotechnology, pharmaceutical and food
industries, in addition to being a daily consideration for academic researchers studying …
industries, in addition to being a daily consideration for academic researchers studying …
Global virus outbreaks: Interferons as 1st responders
BX Wang, EN Fish - Seminars in immunology, 2019 - Elsevier
Outbreaks of severe virus infections with the potential to cause global pandemics are
increasing. In many instances these outbreaks have been newly emerging (SARS …
increasing. In many instances these outbreaks have been newly emerging (SARS …
Filovirus pathogenesis and immune evasion: insights from Ebola virus and Marburg virus
I Messaoudi, GK Amarasinghe, CF Basler - Nature Reviews …, 2015 - nature.com
Ebola viruses and Marburg viruses, members of the filovirus family, are zoonotic pathogens
that cause severe disease in people, as highlighted by the latest Ebola virus epidemic in …
that cause severe disease in people, as highlighted by the latest Ebola virus epidemic in …
Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses
RB Martines, DL Ng, PW Greer… - The Journal of …, 2015 - Wiley Online Library
Ebola viruses and Marburg viruses include some of the most virulent and fatal pathogens
known to humans. These viruses cause severe haemorrhagic fevers, with case fatality rates …
known to humans. These viruses cause severe haemorrhagic fevers, with case fatality rates …
[HTML][HTML] An update on Drug Repurposing: Re-written saga of the drug's fate
Drug repurposing is an unconventional drug discovery approach to explore new therapeutic
benefits of existing, shelved and the drugs in clinical trials. This approach is currently …
benefits of existing, shelved and the drugs in clinical trials. This approach is currently …
[HTML][HTML] Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1
During antiviral defense, interferon (IFN) signaling triggers nuclear transport of tyrosine-
phosphorylated STAT1 (PY-STAT1), which occurs via a subset of karyopherin alpha (KPNA) …
phosphorylated STAT1 (PY-STAT1), which occurs via a subset of karyopherin alpha (KPNA) …
[HTML][HTML] Structure and assembly of the Ebola virus nucleocapsid
W Wan, L Kolesnikova, M Clarke, A Koehler, T Noda… - Nature, 2017 - nature.com
Ebola and Marburg viruses are filoviruses: filamentous, enveloped viruses that cause
haemorrhagic fever. Filoviruses are within the order Mononegavirales, which also includes …
haemorrhagic fever. Filoviruses are within the order Mononegavirales, which also includes …
[HTML][HTML] Ebola virus disease: An emerging and re-emerging viral threat
The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …
Forty-five years of Marburg virus research
In 1967, the first reported filovirus hemorrhagic fever outbreak took place in Germany and
the former Yugoslavia. The causative agent that was identified during this outbreak, Marburg …
the former Yugoslavia. The causative agent that was identified during this outbreak, Marburg …