Invasive and non-invasive therapies for Alzheimer's disease and other amyloidosis

G Pandey, V Ramakrishnan - Biophysical Reviews, 2020 - Springer
Advancements in medical science have facilitated in extending human lives. The increased
life expectancy, though, has come at a cost. The cases of an aging population suffering from …

The SARS-CoV-2 spike protein is vulnerable to moderate electric fields

CR Arbeitman, P Rojas, P Ojeda-May… - Nature …, 2021 - nature.com
Most of the ongoing projects aimed at the development of specific therapies and vaccines
against COVID-19 use the SARS-CoV-2 spike (S) protein as the main target. The binding of …

Tetrazolium/formazan test as an efficient method to determine fungal chitosan antimicrobial activity

SH Moussa, AA Tayel, AA Al-Hassan… - Journal of …, 2013 - Wiley Online Library
Fungal chitosan was extracted from Aspergillus niger mycelia. The produced chitosan was
characterized with deacetylation degree of 89.2%, a molecular weight of 2.4× 104 Da, and …

Dynamics of electron density, spin-phonon coupling, and dielectric properties of nanoparticles at the spin-reorientation temperature: Role of exchange striction

S Chaturvedi, P Shyam, A Apte, J Kumar… - Physical Review B, 2016 - APS
Samarium orthoferrite (SmFe O 3) has been the subject of debate on the existence or
nonexistence of ferroelectric properties. It has a high spin-reorientation transition …

Effect of electric field on α-synuclein fibrils: Revealed by molecular dynamics simulations

J Razzokov, S Fazliev, M Makhkamov… - International Journal of …, 2023 - mdpi.com
The self-association of amylogenic proteins to the fibril form is considered a pivotal factor in
the pathogenesis of neurodegenerative diseases, including Parkinson's disease (PD). PD …

Nanosize effect: Enhanced compensation temperature and existence of magnetodielectric coupling in

S Chaturvedi, P Shyam, R Bag, MM Shirolkar, J Kumar… - Physical Review B, 2017 - APS
In transition metal oxides, quantum confinement arising from a large surface to volume ratio
often gives rise to novel physicochemical properties at nanoscale. Their size-dependent …

Electrospinning induced orientation of protein fibrils

D Chen, N Narayanan, E Federici, Z Yang… - …, 2020 - ACS Publications
Amyloid-like fibrils are prepared from protein in the lab by controlled heat treatments, yet
these must be further assembled to match the desirable mechanical and structural …

Enhancing cell motility via non-contact capacitively coupled electrostatic field

I Zironi, T Cramer, A Fuschi, M Cioni, G Guerra… - Scientific Reports, 2024 - nature.com
Cellular motility is essential for making and maintaining multicellular organisms throughout
their lifespan. Migrating cells can move either individually or collectively by a crawling …

Elucidating the effect of static electric field on amyloid beta 1–42 supramolecular assembly

S Muscat, F Stojceski, A Danani - Journal of Molecular Graphics and …, 2020 - Elsevier
Amyloid-β (Aβ) aggregation is recognized to be a key toxic factor in the pathogenesis of
Alzheimer disease, which is the most common progressive neurodegenerative disorder. In …

Aptamer as a Tool for Investigating the Effects of Electric Field on Aβ40 Monomer and Aggregates Using Single-Molecule Force Spectroscopy

Y Zheng, Q Wang, X Yang, W Nie, L Zou, X Liu… - Analytical …, 2018 - ACS Publications
The effects of electric field (EF) on amyloid proteins have been given increasing attention in
regulation of amyloid-β (Aβ) aggregation and therapeutic methods because of prevalence of …