Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder with few
pharmacological treatments. Minocycline, a tetracycline derivative that inhibits microglial …

Multiple sclerosis (MS) is an immune-mediated disease characterized by inflammation,
demyelination, and neurodegeneration within the central nervous system. Brain plasticity …

Schizophrenia and Autism spectrum disorders (SSD and ASD) are neurodevelopmental
disorders involving cognitive impairment. Timely diagnosis is important for early intervention; …

Introduction A hallmark of photoreceptor degenerations is progressive, aberrant remodeling
of the surviving retinal neurons and glia following photoreceptor loss. The exact relationship …

In retinal degenerative diseases, such as retinitis pigmentosa (RP), the characteristic
photoreceptor cell death is associated with changes of microglia and macroglia cells. Gene …

Continuous lifelong acquisition, updating, and fine-tuning of knowledge and skills is of
crucial significance for the survival of humans. However, current neuromorphic devices …

Inherited retinal degenerative diseases are a prominent cause of blindness. Although
mutations causing death of photoreceptors are mostly known, the pathophysiology …

Objective Retinitis pigmentosa (RP) is a hereditary retinal disease characterized by
progressive photoreceptor degeneration, leading to vision loss. The best hope for a cure for …

Purpose: Leber congenital amaurosis (LCA) is a sight-threatening inherited retinal disorder
(IRD) caused by numerous genetic mutations. Multi-characteristic opsin (MCO)-based …

The majority of inherited retinal degenerative diseases and dry age-related macular
degeneration are characterized by decay of the outer retina and photoreceptors, which …