Complex multicellular life in mammals relies on functional cooperation of different organs for
the survival of the whole organism. The kidneys play a critical part in this process through …

Alloantibodies to HLA class I or II and other antigens expressed by endothelium cause a
variety of effects on renal transplants, ranging from acute to chronic rejection, and even …

We describe the molecular and cellular mechanisms believed to be responsible for the
rejection of renal allografts, including acute T cell–mediated rejection, acute antibody …

Transplant glomerulopathy (TG) is a histologic entity described more than four decades ago.
In the last few years, our understanding of TG has improved significantly. Current evidence …

Acute vascular rejection (AVR) is characterized by immune-mediated vascular injury and
heightened endothelial cell (EC) apoptosis. We reported previously that apoptotic ECs …

The first Banff proposal for the diagnosis of pancreas rejection (Am J Transplant 2008; 8:
237) dealt primarily with the diagnosis of acute T-cell-mediated rejection (ACMR), while only …

Improvements in anti-HLA antibody detection and diagnostic criteria have increased
recognition of antibody-mediated rejection (AMR) following renal transplantation. Therapy of …

The identification of suitable donor kidneys for transplant candidates with high levels of
circulating antibodies against human leukocyte antigen (HLA) is a major challenge and …

The nonspecific diagnoses 'chronic rejection''CAN', or 'IF/TA'suggest neither identifiable
pathophysiologic mechanisms nor possible treatments. As a first step to developing a more …

While glomerulitis is graded according to the Banff classification, no criteria for scoring
peritubular capillaritis (PTC) have been established. We retrospectively applied PTC-scoring …